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Cited by 8Respiratory viral infections researchPediatric health and respiratory diseasesHerbal Medicine Research Studies

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Intranasal ipratropium bromide for the common cold

AlBalawi, Zaina H, Othman, Sahar S, AlFaleh, Khalid·2011·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd008231.pub2
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Abstract

Background The common cold is one of the most common illnesses in humans and constitutes an economic burden both in terms of productivity and expenditure for treatment. There is no proven cure for the common cold and symptomatic relief is the mainstay of treatment. The use of intranasal ipratropium bromide (IB) has been addressed in several studies and might prove an effective treatment for the common cold. Objectives To determine the effect of IB versus placebo or no treatment on severity of rhinorrhoea and nasal congestion in children and adults with the common cold. Subjective overall improvement was another primary outcome and side effects were reported as a secondary outcome. Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL 2011, Issue 1) which contains the Acute Respiratory Infections Group's Specialised Register, MEDLINE (1950 to January week 4, 2011), MEDLINE in-process and other non-indexed citations (February 2011), EMBASE (1974 to February 2011), AMED (1985 to February 2011), Biosis (1974 to February 2011) and LILACS (1985 to February 2011). Selection criteria Randomised controlled trials (RCTs) comparing IB to placebo or no treatment in children and adults with the common cold. Data collection and analysis Two review authors independently extracted data and assessed trial quality. We used a standardised form to extract relevant data and we contacted trial authors for additional information. Main results Seven trials with a to…

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References 28 · Cited by 8

Research works printed but not linked: 25

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Metadata

Authors
AlBalawi, Z. H., Othman, S. S., & AlFaleh, K.
Affiliations
  • King Saud University (SA)
  • King Abdulaziz University (SA)
ORCID
Othman, Sahar S
Venue
Cochrane Database of Systematic Reviews
Publisher
John Wiley & Sons, Ltd
Published
2011-07-06
Issue
7
Pages
CD008231-CD008231
ISSN
1361-6137 (ISSN-L)
DOI
10.1002/14651858.cd008231.pub2
OpenAlex
W4236154037
Cited by
8
References
28
Citations by year
2025: 1 · 2018: 2 · 2013: 4 · 2012: 1
Type
reference entry
Language
en
Update notices
new_version (2013-06-19)
Open access
closed
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric health and respiratory diseases
  • Health Sciences › Medicine › Complementary and alternative medicine › Herbal Medicine Research Studies
Keywords
ipratropium bromide, common cold, rhinorrhea, nasal congestion, symptom relief, adverse effects, epistaxis, nasal dryness, acute respiratory infections, children and adults, treatment efficacy and safety, placebo comparison, economic burden of illness, productivity loss, treatment costs, health-related quality of life
MeSH terms
Administration, Intranasal, Common Cold, Humans, Ipratropium, Nasal Decongestants, Randomized Controlled Trials as Topic

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CoChat. (2026). Citation check: Intranasal ipratropium bromide for the common cold. https://app.cochat.ai/papers/10.1002/14651858.cd008231.pub2
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AlBalawi, Z. H., Othman, S. S., & AlFaleh, K. (2011). Intranasal ipratropium bromide for the common cold. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd008231.pub2