Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus.

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Functional Hydrogels for Treatment of Chronic Wounds

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Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update)

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Integrated sensing and delivery of oxygen for next-generation smart wound dressings

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The discovery and development of topical medicines for wound healing

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Negative pressure wound therapy compared with standard moist wound care on diabetic foot ulcers in real-life clinical practice: results of the German DiaFu-RCT

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Consensus on the application of negative pressure wound therapy of diabetic foot wounds

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Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review

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A systematic review and meta-analysis of efficacy and safety of negative pressure wound therapy in the treatment of diabetic foot ulcer

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Surgical debridement, maggot therapy, negative pressure wound therapy, and silver foam dressing revive hope for patients with diabetic foot ulcer

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Evolving spectrum of diabetic wound: Mechanistic insights and therapeutic targets

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Negative pressure wound therapy in grade 1 and 2 diabetic foot ulcers: A randomized controlled study

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Accelerated infected wound healing by probiotic-based living microneedles with long-acting antibacterial effect

Jin, Y., Lu, Y., Jiang, X., Wang, M., Yuan, Y., Zeng, Y., Guo, L., & Li, W. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.05.008 · Cited by 68

A Clinical Review of Diabetic Foot Infections

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Promoting Re-epithelialization in an oxidative diabetic wound microenvironment using self-assembly of a ROS-responsive polymer and P311 peptide micelles

Shi, R., Li, H., Jin, X., Huang, X. S., Ou, Z., Zhang, X., Luo, G., & Deng, J. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.09.017 · Cited by 65

What’s old is new again: Insights into diabetic foot microbiome

Rajab, A. A. H., & Hegazy, W. A. H. (2023) · World Journal of Diabetes · doi:10.4239/wjd.v14.i6.680 · Cited by 53

Transverse Tibial Bone Transport Enhances Distraction Osteogenesis and Vascularization in the Treatment of Diabetic Foot

Ou, S., Xu, C., Yang, Y., Ya, C., Li, W., Lu, H., Li, G., Sun, H., & Qi, Y. (2022) · Orthopaedic Surgery · doi:10.1111/os.13416 · Cited by 48

Alternative Approaches for the Management of Diabetic Foot Ulcers

Pouget, C., Dunyach‐Remy, C., Pantel, A., Boutet-Dubois, A., Schuldiner, S., Sotto, A., Lavigne, J., & Loubet, P. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.747618 · Cited by 48

Palliative Wound Care

Beers, E. H. (2019) · Surgical Clinics of North America · doi:10.1016/j.suc.2019.06.008 · Cited by 45

Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds

Yu, X., Xu, P., Wang, X., Chen, Y., Zhang, Z., & Zhang, Y. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02116-5 · Cited by 41

Australian guideline on wound healing interventions to enhance healing of foot ulcers: part of the 2021 Australian evidence‐based guidelines for diabetes‐related foot disease

Chen, P., Carville, K., Swanson, T., Lazzarini, P. A., Charles, J., Cheney, J., Prentice, J., & Australian Diabetes‐related Foot Disease Guidelines & Pathways Project (2022) · Journal of Foot and Ankle Research · doi:10.1186/s13047-022-00544-5 · Cited by 40

Negative pressure wound therapy versus usual care in patients with surgical wound healing by secondary intention in the UK (SWHSI-2): an open-label, multicentre, parallel-group, randomised controlled trial

Arundel, C., Mandefield, L., Fairhurst, C. M., Baird, K., Gkekas, A., Saramago, P., Chetter, I. C., Martin, B. C., Hewitt, C. E., Mott, A., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)00143-6 · Cited by 35

Negative pressure wound therapy for managing the open abdomen in non-trauma patients

Cheng, Y., Wang, K., Gong, J., Liu, Z., Gong, J., Zeng, Z., & Wang, X. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013710.pub2 · Cited by 34

Dual-responsive metal polyphenol network nanosheets for diabetic wound healing

Cheng, B., Zhou, J., Wang, X., He, Z., Xu, Z., Wang, J., Chen, J., Zhu, Z., Zhao, W., Wan, Q., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.153071 · Cited by 32

Adipose-Derived Stem Cell Exosomes Facilitate Diabetic Wound Healing: Mechanisms and Potential Applications

Wang, K., Yang, Z., Zhang, B., Gong, S., & Wu, Y. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s466034 · Cited by 34

Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers

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Prognosis of the outcome of severe diabetic foot ulcers with multidisciplinary care

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Effects of different treatment measures on the efficacy of diabetic foot ulcers: a network meta-analysis

Ouyang, H. W., Yang, J., Wan, H., Huang, J., & Yin, Y. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1452192 · Cited by 27

Gynura divaricata (L.) DC. promotes diabetic wound healing by activating Nrf2 signaling in diabetic rats

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Risk factors for diabetic foot ulcers mortality and novel negative pressure combined with platelet-rich plasma therapy in the treatment of diabetic foot ulcers

Wang, Y., Liu, B., Pi, Y., Hu, L., Yuan, Y., Luo, J., Tao, Y., Li, P., Lu, S., & Song, W. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1051299 · Cited by 26

Therapeutic potential of quercetin in diabetic foot ulcer: Mechanistic insight, challenges, nanotechnology driven strategies and future prospects

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Roles of Oxidative Stress and Raftlin in Wound Healing Under Negative-Pressure Wound Therapy

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Negative Pressure Wound Therapy Promotes Wound Healing by Suppressing Macrophage Inflammation in Diabetic Ulcers

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Molecular mechanisms of action of negative pressure wound therapy: a systematic review

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Downregulation of hsa-miR-203 in peripheral blood and wound margin tissue by negative pressure wound therapy contributes to wound healing of diabetic foot ulcers

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Negative-pressure wound therapy compared with advanced moist wound therapy: A comparative study on healing efficacy in diabetic foot ulcers

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Green synthesis of nanoparticles for wound healing

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Local Management for Diabetic Foot Ulcers

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Exploring an Innovative Approach: Integrating Negative-Pressure Wound Therapy with Silver Nanoparticle Dressings in Skin Graft Procedures

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An economic evaluation examining the cost‐effectiveness of continuous diffusion of oxygen therapy for individuals with diabetic foot ulcers

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Negative pressure wound therapy following excision of pilonidal sinus disease: A retrospective review

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Charcot neuro-osteoarthropathy: a review of key concepts and an evidence-based surgical management algorithm

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Effectiveness of negative pressure wound therapy: Minimum five-year follow-up and review of the literature

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Infecção no pé diabético

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Debridement: Technical Considerations and Treatment Options for the Interprofessional Team

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Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue

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Antibiotic-loaded Bone Cement Combined with Vacuum-assisted Closure Facilitating Wound Healing in Wagner 3-4 Diabetic Foot Ulcers

Sun, Y., Li, L., & Zhang, Z. (2022) · The International Journal of Lower Extremity Wounds · doi:10.1177/15347346221109045 · Cited by 17

Negative pressure wound therapy versus usual care for surgical wounds healing by secondary intention (SWHSI-2 trial): study protocol for a pragmatic, multicentre, cross surgical specialty, randomised controlled trial

Chetter, I. C., Arundel, C., Corbacho, B., Hewitt, C. E., Fairhurst, C. M., Joshi, K., Mott, A., Rodgers, S., Saramago, P., Torgerson, D. J., et al. (2021) · Trials · doi:10.1186/s13063-021-05662-2 · Cited by 16

Clinical outcomes of negative pressure wound therapy with instillation vs standard negative pressure wound therapy for wounds: A meta‐analysis of randomised controlled trials

Wang, G., Xu, H., Xu, G., Zhang, H., Li, Z., & Liu, D. (2022) · International Wound Journal · doi:10.1111/iwj.13989 · Cited by 16

Hypoxia-inducible Factor-1α in Diabetic Foot Ulcers: Plain but Not Simple

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Multifunctional Hydrogel of Recombinant Humanized Collagen Loaded with MSCs and MnO2 Accelerates Chronic Diabetic Wound Healing

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Engineering tools for stimulating wound healing

Lazarus, E., Barnum, L., Ramesh, S., Quint, J. P., Samandari, M., Laflamme, S., Secord, T. W., Schmidt, T. A., Tamayol, A., & Rivero, I. V. (2024) · Applied Physics Reviews · doi:10.1063/5.0173663 · Cited by 16

Proteomics changes after negative pressure wound therapy in diabetic foot ulcers

Jia, Z., Liu, L., Zhang, S., Zhao, X., Luo, L., Tang, Y., Shen, B. Q., & Chen, M. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12474 · Cited by 16

Perioperative Complications and Adverse Events after Surgery for Peripheral Nerve- and Para-lumbar Spine Diseases

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The effectiveness of negative-pressure wound therapy for wound healing after stoma reversal: a randomised control study (SR-PICO study)

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Sprayable self-assembled curcumin-metal-polyphenol nanomedicine with anti-inflammatory, ROS-scavenging and pro-angiogenesis effects for promoting diabetic wound healing

Liang, X., Xian, C., Du, J., Huang, X., Yang, Y., Bi, G., Li, X., Gao, M., Wu, M., Wu, J. Y., et al. (2025) · Nano Research · doi:10.26599/nr.2025.94908001 · Cited by 14

Wound Assessment Using Bates Jensen Wound Assessment Tool in Acute Musculoskeletal Injury Following Low-Cost Wall-Mounted Negative-Pressure Wound Therapy Application

Gupta, S. K., Srivastava, A., Malhotra, R., Chadha, M., & Aggarwal, A. (2023) · Indian Journal of Orthopaedics · doi:10.1007/s43465-023-00861-2 · Cited by 14

A Comparative Study on Efficacy of Negative Pressure Wound Therapy Versus Standard Wound Therapy for Patients With Compound Fractures in a Tertiary Care Hospital

Kumaar, A., Shanthappa, A. H., & Ethiraj, P. (2022) · Cureus · doi:10.7759/cureus.23727 · Cited by 14

Update on the impact of lipid and glucose control on diabetic wound healing

Rui, S., Xu, Y., Ji, Z., Li, X., Tao, Z., Luo, W., Yao, Y., Chen, L., & Ma, G. (2025) · Metabolism Open · doi:10.1016/j.metop.2025.100408 · Cited by 12

The effectiveness of negative-pressure wound therapy for wound healing after stoma reversal: a randomized control study

Kang, S. I., & Kim, S. (2023) · Annals of Surgical Treatment and Research · doi:10.4174/astr.2023.105.3.126 · Cited by 12

Advancements, applications, and safety of negative pressure wound therapy: a comprehensive review of its impact on wound outcomes

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Management of Diabetic Wounds: Expert Panel Consensus Statement

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Severe complications after negative pressure wound therapy in burned wounds: two case reports

Ren, H., & Li, Y. (2014) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s66117 · Cited by 12

Evidence map of recommendations on diabetic foot ulcers care：A systematic review of 22 guidelines

Sun, Y., Ma, L., Ji, M., & Wang, Z. (2022) · Journal of Tissue Viability · doi:10.1016/j.jtv.2022.03.001 · Cited by 13

Treatment of diabetic foot ulcers

Ahn, J. (2021) · Journal of Korean Medical Association · doi:10.5124/jkma.2021.64.8.529 · Cited by 12

Correlation between inflammatory factors, autophagy protein levels, and infection in granulation tissue of diabetic foot ulcer

Deng, L., Wang, G., & Ju, S. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1233 · Cited by 10

A prospective multicenter phase III clinical trial evaluating the efficacy and safety of silk elastin sponge in patients with skin defects

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Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial

Melamed, E. A., Dabbah, J., Israel, T., Kan, I., Pinzur, M. S., Roth, T., & Borkow, G. (2025) · Advances in Wound Care · doi:10.1089/wound.2024.0273 · Cited by 10

Comparison and evaluation of negative pressure wound therapy versus standard wound care in the treatment of diabetic foot ulcers

Guo, Q. (2025) · BMC Surgery · doi:10.1186/s12893-025-02885-x · Cited by 10

Modern therapeutic options in diabetic foot ulcer

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Negative pressure wound therapy for managing the open abdomen in non-trauma patients

Cheng, Y., Gong, J., Liu, Z., Gong, J., & Zeng, Z. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013710 · Cited by 10

Negative pressure wound therapy: clinical utility

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ALGINATE versus NPWT in the Preparation of Surgical Excisions for an STSG: ATEC Trial

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