The DOI matches its Crossref record.
A comparison of RNA with DNA in template-directed synthesis
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Claims other papers make about this one
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In the citing paper
“This study suggests that the nonenzymatic kinetic rates for RNAs may have higher and values than for DNAs.”
From Thermodynamic Basis for the Emergence of Genomes during Prebiotic Evolution (2012) · cites this paper as [51]
In the citing paper
“Prior work had found that the non-enzymatic copying of RNA differed from that of DNA in at least two respects: 1) reaction rates of RNA were higher, and 2) prominent G:U wobble pairing led to higher mutation rates in RNA.3,20,30”
From Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences (2013) · cites this paper as [30]
In the citing paper
“Another effect of local structure is that RNA polymerization reactions have a different mutation profile than the corresponding reactions with DNA, with G-U wobble pairing causing high mutation rates for RNA.20,30”
From Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences (2013) · cites this paper as [30]
In the citing paper
“This corroborates previous observations that the G:U wobble pair is a greater source of error when copying RNA compared to the G:T wobble pair in DNA (46).”
From The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA (2011) · cites this paper as [46]
Citations
Cited by
Sorted by citations
Prebiotic chemistry and the origin of the RNA world.
Leslie E., O. (2004) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230490460765 · Cited by 1,124
Serine Octamers: Cluster Formation, Reactions, and Implications for Biomolecule Homochirality
Nanita, S. C., & Cooks, R. G. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200501328 · Cited by 184
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA
Leu, K., Obermayer, B., Rajamani, S., Gerland, U., & Chen, I. A. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr525 · Cited by 85
Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences
Leu, K., Kervio, E., Obermayer, B., Turk-MacLeod, R. M., Yuan, C., Luevano, J.-M., Chen, E., Gerland, U., Richert, C., & Chen, I. A. (2013) · Journal of the American Chemical Society · doi:10.1021/ja3095558 · Cited by 78
Templating efficiency of naked DNA
Kervio, E., Hochgesand, A., Steiner, U. E., & Richert, C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914872107 · Cited by 62
Metadata
- Authors
- Zielinski, M., Kozlov, I. A., & Orgel, L. E.
- Venue
- Helvetica Chimica Acta
- Published
- 2000
- References
- 0
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: A comparison of RNA with DNA in template-directed synthesis. https://app.cochat.ai/papers/10.1002/1522-2675(20000809)83:8
- The paper
- Zielinski, M., Kozlov, I. A., & Orgel, L. E. (2000). A comparison of RNA with DNA in template-directed synthesis. Helvetica Chimica Acta. https://doi.org/10.1002/1522-2675(20000809)83%3A8
