Radial glia in the ventral telencephalon
Open accessAbstract
The ventral telencephalon is the developmental origin of the basal ganglia and the source of neuronal and glial cells that integrate into developing circuits in other areas of the brain. Radial glia in the embryonic subpallium give rise to an enormous diversity of mature cell types, either directly or through other transit‐amplifying progenitors. Here, we review current knowledge about these subpallial neural stem cells and their progeny, focusing on the period of neurogenesis. We describe their cell biological features and the extrinsic and intrinsic molecular codes that guide their fate specification in defined temporal and spatial sequences. We also discuss the role of clonal lineage in the organization and specification of mature neurons.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The Subpallium-GABA neighbourhood (subclasses 39-90, total 1,051 clusters) was divided into 7 classes that are likely related to their distinct developmental origins.
“On the basis of the molecular signature and regional specificity of each subclass, the Subpallium-GABA neighbourhood (subclasses 39–90, total 1,051 clusters) was divided into 7 classes that are likely related to their distinct developmental origins29,30”
From A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain (2023) · cites this paper as [30]
The Introduction says subpallial cell diversity varies with germinal zone and developmental timing, supporting the general link between cell types and developmental origins. The source does not report a Subpallium-GABA neighbourhood, subclasses 39–90, 1,051 clusters, or a division into seven classes. The indexed passages have section labels but no page numbers. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 164 · Cited by 62
- Authors
- Turrero García, M., & Harwell, C. C.
- Affiliations
- Department of Neurobiology Harvard Medical School Boston MA USA
- Harvard University (US)
- Corresponding author
- Harwell, Corey C.
- ORCID
- Harwell, Corey C.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2017-09-19
- Volume
- 591
- Issue
- 24
- Pages
- 3942-3959
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- PMC
- PMC5747302
- OpenAlex
- W2753261993
- Cited by
- 62
- References
- 164
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 4 · 2023: 11 · 2022: 9 · 2021: 10 · 2020: 7 · 2019: 6 · 2018: 3 · 2017: 1
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (K01NS089720, R01NS102228)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- radial glia, ventral telencephalon, subpallium, basal ganglia, neural stem cells, neurogenesis, cell fate specification, clonal lineages
- MeSH terms
- Animals, Cell Differentiation, Humans, Neuroglia, Neurons, Telencephalon, Cell Lineage, Neurogenesis, Neural Stem Cells, Ependymoglial Cells
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
