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Management of Fulminant Hepatic Failure
Abstract
Fulminant hepatic failure, a syndrome characterized by multiorgan dysfunction precipitated by acute liver injury in the absence of pre-existing liver disease, represents a unique management challenge. Efforts should be directed to three main goals: (1) identification of the precipitating cause, both to permit the use of disease-specific treatments and to aid in the estimation of prognosis and the appropriateness and timing of transplantation; (2) institution of supportive and prophylactic care measures, usually in the intensive care setting; and (3) determination of the timing of referral for emergency liver transplantation.
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Citations
Cited by
Controlled trials of charcoal hemoperfusion and prognostic factors in fulminant hepatic failure
O'Grady, J. G., Gimson, A. E. S., O'Brien, C. J., Pucknell, A., Hughes, R. D., & Williams, R. (1988) · Gastroenterology · doi:10.1016/0016-5085(88)90011-x · Cited by 538
Harrison, P. M., Keays, R., Bray, G. P., Alexander, G. J. M., & Williams, R. (1990) · The Lancet · doi:10.1016/0140-6736(90)91388-q · Cited by 398
Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient*
Kato, T., Furusaka, A., Miyamoto, M., Date, T., Yasui, K., Hiramoto, J., Nagayama, K., Tanaka, T., & Wakita, T. (2001) · Journal of Medical Virology · doi:10.1002/jmv.1055 · Cited by 255
Stravitz, R. T., Fontana, R. J., Meinzer, C., Durkalski‐Mauldin, V., Hanje, A. J., Olson, J., Koch, D., Hamid, B., Schilsky, M. L., McGuire, B., et al. (2021) · Hepatology · doi:10.1002/hep.31767 · Cited by 50
Metadata
- Authors
- Lilly, L. B.
- Venue
- Hepatology: Diagnosis and Clinical Management
- Publisher
- Wiley
- Published
- 2012-09-04
- Pages
- 132-141
- OpenAlex
- W1521799634
- Cited by
- 186
- References
- 0
- Type
- other
- Language
- en
- Open access
- closed
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- Lilly, L. B. (2012). Management of Fulminant Hepatic Failure. Hepatology: Diagnosis and Clinical Management. https://doi.org/10.1002/9781118314968.ch10
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
