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Uniform Rattle‐type Hollow Magnetic Mesoporous Spheres as Drug Delivery Carriers and their Sustained‐Release Property
Abstract
A novel kind of rattle‐type hollow magnetic mesoporous sphere (HMMS) with Fe 3 O 4 particles encapsulated in the cores of mesoporous silica microspheres has been successfully fabricated by sol–gel reactions on hematite particles followed by cavity generation with hydrothermal treatment and H 2 reduction. Such a structure has the merits of both enhanced drug‐loading capacity and a significant magnetization strength. The prepared HMMSs realize a relatively high storage capacity up to 302 mg g−1 when ibuprofen is used as a model drug, and the IBU–HMMS system has a sustained‐release property, which follows a Fick's law.
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Citations
Cited by
Hollow‐Structured Mesoporous Materials: Chemical Synthesis, Functionalization and Applications
Li, Y., & Shi, J. (2014) · Advanced Materials · doi:10.1002/adma.201305319 · Cited by 759
Self-citationPalanikumar, L., Choi, E. S., Cheon, J. Y., Joo, S. H., & Ryu, J. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201402755 · Cited by 150
Wang, H., Kawaguchi, K., Pyatenko, A., Li, X., Swiatkowska‐Warkocka, Z., Katou, Y., & Koshizaki, N. (2012) · Chemistry – A European Journal · doi:10.1002/chem.201102079 · Cited by 60
Magnetically separable carbon capsules loaded with laccase and their application to dye degradation
Valle-Vigón, P., & Fuertes, A. B. (2011) · RSC Advances · doi:10.1039/c1ra00333j · Cited by 18
Metadata
- Authors
- Zhao, W., Chen, H., Li, Y., Li, L., Lang, M., & Shi, J.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2008-09-16
- Volume
- 18
- Issue
- 18
- Pages
- 2780-2788
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W1993044435
- Cited by
- 430
- References
- 0
- FWCI
- 18.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhao, W., Chen, H., Li, Y., Li, L., Lang, M., & Shi, J. (2008). Uniform Rattle‐type Hollow Magnetic Mesoporous Spheres as Drug Delivery Carriers and their Sustained‐Release Property. Advanced Functional Materials. https://doi.org/10.1002/adfm.200701317
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