The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A Shape‐Adaptive, Antibacterial‐Coating of Immobilized Quaternary‐Ammonium Compounds Tethered on Hyperbranched Polyurea and its Mechanism of Action
Open accessAbstract
Quaternary‐ammonium‐compounds are potent cationic antimicrobials used in everyday consumer products. Surface‐immobilized, quaternary‐ammonium‐compounds create an antimicrobial contact‐killing coating. We describe the preparation of a shape‐adaptive, contact‐killing coating by tethering quaternary‐ammonium‐compounds onto hyperbranched polyurea coatings, able to kill adhering bacteria by partially enveloping them. Even after extensive washing, coatings caused high contact‐killing of Staphylococcus epidermidis, both in culture‐based assays and through confocal‐laser‐scanning‐microscopic examination of the membrane‐damage of adhering bacteria. In culture‐based assays, at a challenge of 1600 CFU/cm 2, contact‐killing was >99.99%. The working‐mechanism of dissolved quaternary‐ammonium‐compounds is based on their interdigitation in bacterial membranes, but it is difficult to envisage how immobilized quaternary‐ammonium‐molecules can exert such a mechanism of action. Staphylococcal adhesion forces to hyperbranched quaternary‐ammonium coatings were extremely high, indicating that quaternary‐ammonium‐molecules on hyperbranched polyurea partially envelope adhering bacteria upon contact. These lethally strong adhesion forces upon adhering bacteria then cause removal of membrane lipids and eventually lead to bacterial death.
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Cites
Polymeric coatings that inactivate both influenza virus and pathogenic bacteria
Haldar, J., An, D., Álvarez de Cienfuegos, L., Chen, J., & Klibanov, A. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608803103 · Cited by 297
Antibacterial activity of bactericide-immobilized filler for resin-based restoratives
Imazato, S. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00217-5 · Cited by 196
Beyth, N., Yudovin-Farber, I., Perez-Davidi, M., Domb, A. J., & Weiss, E. I. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010341107 · Cited by 192
Microbiologic environment of the conventional operating room
Fitzgerald, R. H. (1979) · Archives of Surgery · doi:10.1001/archsurg.1979.01370310014003 · Cited by 64
Cited by
Surface modifications for antimicrobial effects in the healthcare setting: a critical overview
Adlhart, C., Verran, J., Azevedo, N. F., Olmez, H., Keinänen-Toivola, M. M., Gouveia, I., Melo, L. F., & Crijns, F. (2018) · Journal of Hospital Infection · doi:10.1016/j.jhin.2018.01.018 · Cited by 308
Current developments in antimicrobial surface coatings for biomedical applications
Swartjes, J. J. T. M., Sharma, P. K., Kooten, T. G., Mei, H. C., Mahmoudi, M., Busscher, H. J., & Rochford, E. T. J. (2015) · Current Medicinal Chemistry · doi:10.2174/0929867321666140916121355 · Cited by 149
Effect of anti-biofilm glass–ionomer cement on Streptococcus mutans biofilms
Wang, S.-P., Ge, Y., Zhou, X.-D., Xu, H. H., Weir, M. D., Zhang, K.-K., Wang, H.-H., Hannig, M., Rupf, S., Li, Q., et al. (2016) · International Journal of Oral Science · doi:10.1038/ijos.2015.55 · Cited by 80
Antibacterial and biofilm-disrupting coatings from resin acid-derived materials
Ganewatta, M. S., Miller, K. P., Singleton, S. P., Mehrpouya-Bahrami, P., Chen, Y. P., Yan, Y., Nagarkatti, M., Nagarkatti, P., Decho, A. W., & Tang, C. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b01005 · Cited by 84
Self-citationCavallaro, A., Mierczynska, A., Barton, M., Majewski, P., & Vasilev, K. (2016) · Biofouling · doi:10.1080/08927014.2015.1115977 · Cited by 55
Metadata
- Authors
- Asri, L. A. T. W., Crismaru, M., Roest, S., Chen, Y., Ivashenko, O., Rudolf, P., Tiller, J. C., van der Mei, H. C., Loontjens, T. J. A., & Busscher, H. J.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2013-08-08
- Volume
- 24
- Issue
- 3
- Pages
- 346-355
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2147909536
- Cited by
- 332
- References
- 4
- FWCI
- 9.19
- Type
- journal article
- Language
- en
- Open access
- green
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- Asri, L. A. T. W., Crismaru, M., Roest, S., Chen, Y., Ivashenko, O., Rudolf, P., Tiller, J. C., van der Mei, H. C., Loontjens, T. J. A., & Busscher, H. J. (2014). A Shape‐Adaptive, Antibacterial‐Coating of Immobilized Quaternary‐Ammonium Compounds Tethered on Hyperbranched Polyurea and its Mechanism of Action. Advanced Functional Materials. https://doi.org/10.1002/adfm.201301686
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
