The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
High‐Strength and High‐Toughness Double‐Cross‐Linked Cellulose Hydrogels: A New Strategy Using Sequential Chemical and Physical Cross‐Linking
Abstract
Polysaccharide‐based hydrogels have multiple advantages because of their inherent biocompatibility, biodegradability, and non‐toxicic properties. The feasibility of using polysaccharide‐based hydrogels could be improved if they could simultaneously fulfill the mechanical property and cell compatibility requirements for practical applications. Herein, the construction of double‐cross‐linked (DC) cellulose hydrogels is described using sequential chemical and physical cross‐linking, resulting in DC cellulose hydrogels that are mechanically superior to single‐cross‐linked cellulose hydrogels. The formation and spatial distribution of chemically cross‐linked domains and physically cross‐linked domains within the DC cellulose hydrogels are demonstrated. The molar ratio of epichlorohydrin to anhydroglucose units of cellulose and the concentration of the aqueous ethanol solution are two critical parameters for obtaining mechanically strong and tough DC cellulose hydrogels. The mechanical properties of the DC cellulose hydrogels under loading‐unloading cycles are described using compression and tension models. The possible toughening mechanism of double‐cross‐linking is discussed.
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Cites
Hydrogels for tissue engineering: scaffold design variables and applications
Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136
On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772
On the mechanism of dissolution of cellulose
Lindman, B., Karlström, G., & Stigsson, L. (2010) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2010.04.016 · Cited by 792
“Nonswellable” Hydrogel Without Mechanical Hysteresis
Kamata, H., Akagi, Y., Kayasuga-Kariya, Y., Chung, U.-I., & Sakai, T. (2014) · Science · doi:10.1126/science.1247811 · Cited by 669
Cited by
Liao, H., Guo, X., Wan, P., & Yu, G. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201904507 · Cited by 828
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Recent Progress in High‐Strength and Robust Regenerated Cellulose Materials
Tu, H., Zhu, M., Duan, B., & Zhang, L. (2021) · Advanced Materials · doi:10.1002/adma.202000682 · Cited by 566
Self-citationInorganic Salts Induce Thermally Reversible and Anti‐Freezing Cellulose Hydrogels
Zhang, X., Ma, X., Hou, T., Guo, K., Yin, J., Wang, Z., Shu, L., He, M., & Yao, J. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201902578 · Cited by 530
Bioinspired fabrication of high strength hydrogels from non-covalent interactions
Wang, W., Zhang, Y., & Liu, W. (2017) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2017.04.001 · Cited by 517
Metadata
- Authors
- Zhao, D., Huang, J., Zhong, Y., Li, K., Zhang, L., & Cai, J.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2016-07-04
- Volume
- 26
- Issue
- 34
- Pages
- 6279-6287
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2473081500
- Cited by
- 539
- References
- 4
- FWCI
- 16.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhao, D., Huang, J., Zhong, Y., Li, K., Zhang, L., & Cai, J. (2016). High‐Strength and High‐Toughness Double‐Cross‐Linked Cellulose Hydrogels: A New Strategy Using Sequential Chemical and Physical Cross‐Linking. Advanced Functional Materials. https://doi.org/10.1002/adfm.201601645
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