The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Human Skin 3D Bioprinting Using Scaffold‐Free Approach
Abstract
Organ in vitro synthesis is one of the last bottlenecks between tissue engineering and transplantation of synthetic organs. Bioprinting has proven its capacity to produce 3D objects composed of living cells but highly organized tissues such as full thickness skin (dermis + epidermis) are rarely attained. The focus of the present study is to demonstrate the capability of a newly developed ink formulation and the use of an open source printer, for the production of a really complete skin model. Proofs are given through immunostaining and electronic microscopy that the bioprinted skin presents all characteristics of human skin, both at the molecular and macromolecular level. Finally, the printability of large skin objects is demonstrated with the printing of an adult‐size ear.
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“their composition and culture conditions vary greatly from lab to lab, which can affect interpretation of similar experiments.”
From Single-cell transcriptomics of human-skin-equivalent organoids (2023) · cites this paper as [16]
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Metadata
- Authors
- Pourchet, L. J., Thepot, A., Albouy, M., Courtial, E. J., Boher, A., Blum, L. J., & Marquette, C. A.
- Affiliations
- Lyon 1 Université (FR)
- Hôpital Edouard Herriot (FR)
- 3d.FAB, Univ Lyon Université Lyon1 CNRS, INSA, CPE‐Lyon ICBMS UMR 5246, 43, Bd du 11 novembre 1918 69622 Villeurbanne cedex France
- Corresponding author
- Marquette, Christophe A.
- Venue
- Advanced Healthcare Materials
- Publisher
- Wiley
- Published
- 2016-12-15
- Volume
- 6
- Issue
- 4
- Pages
- 1601101
- ISSN
- 2192-2640 (ISSN-L)
- 2192-2659
- OpenAlex
- W2561559726
- Cited by
- 352
- References
- 17
- Citations by year
- 2026: 18 · 2025: 26 · 2024: 39 · 2023: 40 · 2022: 47 · 2021: 51 · 2020: 37 · 2019: 45 · 2018: 32 · 2017: 16
- FWCI
- 14.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Healthcare Materials (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Nanomaterials and Printing Technologies
- Keywords
- full-thickness skin, open-source 3D printer, skin model, printability, tissue engineering
- MeSH terms
- Epidermal Cells, Animals, Ear, Epidermis, Humans, Dermis, NIH 3T3 Cells, Mice, Printing, Three-Dimensional
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