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Synthesis of Magnetic Microspheres with Immobilized Metal Ions for Enrichment and Direct Determination of Phosphopeptides by Matrix‐Assisted Laser Desorption Ionization Mass Spectrometry
Open accessAbstract
Core/shell structured magnetic silica microspheres with immobilized Fe3+ (see image) are prepared with a simple method. Using a magnetic field, the microspheres are quickly, efficiently, and specifically enriched. Phosphopeptide identification can then be achieved through mass spectroscopy. This is a new method for the enrichment of phosphopeptides and opens up the possibility of other new applications using the microspheres.
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Shen, J.-M., Xu, L., Lu, Y., Cao, H.-M., Xu, Z.-G., Chen, T., & Zhang, H.-X. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.01.059 · Cited by 75
Metadata
- Authors
- Xu, X., Deng, C., Gao, M., Yu, W., Yang, P., & Zhang, X.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2006-12-11
- Volume
- 18
- Issue
- 24
- Pages
- 3289-3293
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W1982185159
- Cited by
- 357
- References
- 0
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- hybrid
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