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Dendrimer‐Functionalized Shell‐crosslinked Iron Oxide Nanoparticles for In‐Vivo Magnetic Resonance Imaging of Tumors

Open access
Shi, Xiangyang, Wang, Su He, Swanson, Scott D., Ge, Song, Cao, Zhengyi, Van Antwerp, Mary E., Landmark, Kevin J., Baker, James R.·2008·Advanced Materials

Abstract

A powerful magnetic nanoprobe with folic acid (FA)-targeting ligands is fabricated by dendrimer functionalization of Fe3O4 nanoparticles (NPs) precoated with crosslinkable and biocompatible polymer multilayer shells. This magnetic probe allows for magnetic resonance imaging of FA receptor-overexpressing tumor cells in vitro and of an early-stage tumor model in vivo (see picture).

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Metadata

Authors
Shi, X., Wang, S. H., Swanson, S. D., Ge, S., Cao, Z., Van Antwerp, M. E., Landmark, K. J., & Baker, J. R.
Venue
Advanced Materials
Publisher
Wiley
Published
2008-05-05
Volume
20
Issue
9
Pages
1671-1678
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2046883852
Cited by
276
References
0
FWCI
17.69
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Dendrimer‐Functionalized Shell‐crosslinked Iron Oxide Nanoparticles for In‐Vivo Magnetic Resonance Imaging of Tumors. https://app.cochat.ai/papers/10.1002/adma.200702770
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Shi, X., Wang, S. H., Swanson, S. D., Ge, S., Cao, Z., Van Antwerp, M. E., Landmark, K. J., & Baker, J. R. (2008). Dendrimer‐Functionalized Shell‐crosslinked Iron Oxide Nanoparticles for In‐Vivo Magnetic Resonance Imaging of Tumors. Advanced Materials. https://doi.org/10.1002/adma.200702770

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