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The Digital Revolution: A New Paradigm for Microfluidics
Abstract
The digital revolution has come to microfluidics. In digital microfluidics (DMF), discrete droplets are manipulated by applying electrical fields to an array of electrodes. In contrast to microchannels, in DMF each sample and reagent is individually addressable, which facilitates exquisite control over chemical reactions. Here, we review the state‐of‐the‐art in DMF, with a discussion of device formats, actuation physics, and biological and nonbiological applications. Along the way, we identify the key players in the field, and speculate on the advances and challenges that lie ahead. As with other fronts in the digital revolution, there have been and will be unexpected developments as DMF matures, but we posit that the future is bright for this promising technology.
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Cited by
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Sun, Q., Wang, D., Li, Y., Zhang, J., Ye, S., Cui, J., Chen, L., Wang, Z., Butt, H.-J., Vollmer, D., et al. (2019) · Nature Materials · doi:10.1038/s41563-019-0440-2 · Cited by 631
Droplet microfluidics: recent developments and future applications
Casadevall i Solvas, X., & deMello, A. (2011) · Chem. Commun. · doi:10.1039/c0cc02474k · Cited by 353
Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine
Jebrail, M. J., Bartsch, M. S., & Patel, K. D. (2012) · Lab on a Chip · doi:10.1039/c2lc40318h · Cited by 324
Moshksayan, K., Kashaninejad, N., Warkiani, M. E., Lock, J. G., Moghadas, H., Firoozabadi, B., Saidi, M. S., & Nguyen, N.-T. (2018) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2018.01.223 · Cited by 267
Choi, K., Kim, J.-Y., Ahn, J.-H., Choi, J.-M., Im, M., & Choi, Y.-K. (2012) · Lab on a Chip · doi:10.1039/c2lc21203j · Cited by 77
Metadata
- Authors
- Abdelgawad, M., & Wheeler, A. R.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2009-02-19
- Volume
- 21
- Issue
- 8
- Pages
- 920-925
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W1987882618
- Cited by
- 382
- References
- 0
- FWCI
- 19.42
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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