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Cited by 187

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Aptamer‐Functionalized Barcode Particles for the Capture and Detection of Multiple Types of Circulating Tumor Cells

Zheng, Fuyin, Cheng, Yao, Wang, Jie, Lu, Jie, Zhang, Bin, Zhao, Yuanjin, Gu, Zhongze·2014·Advanced Materials

Abstract

Aptamer-functionalized barcode particles are employed to capture and detect various types of circulating tumor cells (CTCs). The particles are spherical colloidal crystal clusters, and the reflection properties that arise from their structures are how their codes are evaluated. Aptamer functionalization (with TD05, Sgc8, and Sgd5) make the particles interact with specific CTC types; dendrimers are used to amplify the effect of the aptamers, allowing for increased sensitivity, reliability, and specificity in CTC capture, detection, and subsequent release.

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Metadata

Authors
Zheng, F., Cheng, Y., Wang, J., Lu, J., Zhang, B., Zhao, Y., & Gu, Z.
Venue
Advanced Materials
Publisher
Wiley
Published
2014-09-23
Volume
26
Issue
43
Pages
7333-7338
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2104585673
Cited by
187
References
0
FWCI
7.79
Type
journal article
Language
en
Open access
closed

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Zheng, F., Cheng, Y., Wang, J., Lu, J., Zhang, B., Zhao, Y., & Gu, Z. (2014). Aptamer‐Functionalized Barcode Particles for the Capture and Detection of Multiple Types of Circulating Tumor Cells. Advanced Materials. https://doi.org/10.1002/adma.201403530

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