Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses

Paunovska, Kalina, Da Silva Sanchez, Alejandro J., Sago, Cory D., Gan, Zubao, Lokugamage, Melissa P., Islam, Fatima Z., Kalathoor, Sujay, Krupczak, Brandon R. +1 more·2019·Advanced Materials

Cited by (205)

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    Ricarda C. Steffens, Ernst Wagner · 2022 · Pharmaceutical Research
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    Seigo Kimura, Hideyoshi Harashima · 2023 · Journal of Controlled Release
  3. Cancer Nanomedicines in an Evolving Oncology Landscape
    Peng Guo, Jing Huang, Marsha A. Moses · 2020 · Trends in Pharmacological Sciences
  4. Computational and Experimental Approaches to Investigate Lipid Nanoparticles as Drug and Gene Delivery Systems
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  5. Performance of nanoparticles for biomedical applications: The in vitro / in vivo discrepancy
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  9. An overview of lipid constituents in lipid nanoparticle mRNA delivery systems
    Shiqi Wu, Lixin Lin, Lu Shi, Shuai Liu · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  10. In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting
    Mina Yazdi, Jana Pöhmerer, Morteza Hasanzadeh Kafshgari, Johanna Seidl, Melina Grau, Miriam Höhn, Victoria Vetter, Cosima C. Hoch, Barbara Wollenberg, Gabriele Multhoff et al. · 2024 · Small
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  14. Pancreas-targeted lipid nanoparticles for relatively non-invasive interleukin-12 mRNA therapy in orthotopic pancreatic ductal adenocarcinoma
    Qian Shen, Jia Liu, Ling Zeng, Yupeng Ren, Jing Liao, Sijie Chen, Yingsen Tang, Zixi Zhang, Meng Jiang, Hangping Liao et al. · 2025 · Journal of Controlled Release
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  16. Harnessing Topology and Stereochemistry of Glycidylamine‐Derived Lipid Nanoparticles for in Vivo mRNA Delivery to Immune Cells in Spleen and Their Application for Cancer Vaccination
    Mahmoud M. Abd Elwakil, Ryota Suzuki, Alaa M. Khalifa, Rania M. Elshami, Takuya Isono, Yaser Hosny Ali Elewa, Yusuke Sato, Takashi Nakamura, Toshifumi Satoh, Hideyoshi Harashima · 2023 · Advanced Functional Materials
  17. Developing mRNA Nanomedicines with Advanced Targeting Functions
    Ji Wang, Lijun Cai, Ning Li, Zhiqiang Luo, Haozhen Ren, Bing Zhang, Yuanjin Zhao · 2025 · Nano-Micro Letters
  18. Design principles of lipid nanoparticles for RNA delivery
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  19. Increased PIP3 activity blocks nanoparticle mRNA delivery
    Kalina Paunovska, Alejandro Da Silva Sanchez, Matthew T. Foster, David Loughrey, Emmeline L. Blanchard, Fatima Z. Islam, Zubao Gan, Athanasios Mantalaris, Philip J. Santangelo, James E. Dahlman · 2020 · Science Advances
  20. Lipid nanoparticle screening in nonhuman primates with minimal loss of life
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  21. A tale of nucleic acid–ionizable lipid nanoparticles: Design and manufacturing technology and advancement
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  26. Advances in non-viral mRNA delivery to the spleen
    Eshan A. Narasipura, Owen S. Fenton · 2024 · Biomaterials Science
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    Jiayu Gu, Zhourui Xu, Qiqi Liu, Shiqi Tang, Wenguang Zhang, Shouxia Xie, Xiaoyan Chen, Jiajie Chen, Ken‐Tye Yong, Chengbin Yang et al. · 2023 · Advanced Healthcare Materials
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  55. Hydatidiform mole: a vascular congenital anomaly.
    S. R. M. Reynolds · 1976 · PubMed
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  91. Liposomes as DNA, mRNA and oligonucleotide delivery vectors
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