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Cited by 310

The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.

Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3‐Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a “Green” Solvent

Sharghi, Hashem, Khalifeh, Reza, Doroodmand, Mohammad Mahdi·2009·Advanced Synthesis & Catalysis

Abstract

A one‐pot procedure for synthesis of 1,2,3‐triazole derivatives via the three‐component coupling (TCC) reaction between terminal alkynes, benzyl or alkyl halides, and sodium azide in the presences of 1 mol% nanoparticles copper/carbon (Cu/C) catalyst has been developed. The catalyst showed high catalytic activity and 1,4‐regioselectivity for the [3+2] Huisgen cycloaddition in water as a “green” solvent and good to excellent yields were obtained in all cases. This procedure eliminates the need to handle organic azides, and they are generated in situ. The reaction has a broad scope and is especially practical for the synthesis of new azacrown ether and anthraquinone derivatives of triazole. The heterogeneous catalysts were fully characterized by scanning electron microscopy (SEM), atomic forced microscopy (AFM), X‐ray diffraction (XRD), inductively coupled plasma (ICP) analysis and FT‐IR experimental techniques. The catalyst was recycled ten times without significant loss of activity.

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Metadata

Authors
Sharghi, H., Khalifeh, R., & Doroodmand, M. M.
Venue
Advanced Synthesis & Catalysis
Publisher
Wiley
Published
2009-01
Volume
351
Issue
1-2
Pages
207-218
ISSN
  • 1615-4150 (ISSN-L)
  • 1615-4169
OpenAlex
W2114731897
Cited by
310
References
36
FWCI
8.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3‐Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a “Green” Solvent. https://app.cochat.ai/papers/10.1002/adsc.200800612
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Sharghi, H., Khalifeh, R., & Doroodmand, M. M. (2009). Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3‐Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a “Green” Solvent. Advanced Synthesis & Catalysis. https://doi.org/10.1002/adsc.200800612

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