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Cited by 160

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid‐Catalysed Pictet–Spengler Reactions of Isatins

Duce, Sara, Pesciaioli, Fabio, Gramigna, Lucia, Bernardi, Luca, Mazzanti, Andrea, Ricci, Alfredo, Bartoli, Giuseppe, Bencivenni, Giorgio·2011·Advanced Synthesis & Catalysis

Abstract

The first catalytic asymmetric Pictet–Spengler reaction of isatins is presented. BINOL‐derived phosphoric acids were found to be competent catalysts for this transformation, giving challenging spirooxindole structures bearing a quaternary stereocentre with generally good results. The 1,2,3,4‐tetrahydro‐β‐carboline products (spiroindolinones) are the core of some newly discovered anti‐malarial agents.

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Metadata

Authors
Duce, S., Pesciaioli, F., Gramigna, L., Bernardi, L., Mazzanti, A., Ricci, A., Bartoli, G., & Bencivenni, G.
Venue
Advanced Synthesis & Catalysis
Publisher
Wiley
Published
2011-04-12
Volume
353
Issue
6
Pages
860-864
ISSN
  • 1615-4150 (ISSN-L)
  • 1615-4169
OpenAlex
W2055375413
Cited by
160
References
2
FWCI
11.22
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid‐Catalysed Pictet–Spengler Reactions of Isatins. https://app.cochat.ai/papers/10.1002/adsc.201100050
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Duce, S., Pesciaioli, F., Gramigna, L., Bernardi, L., Mazzanti, A., Ricci, A., Bartoli, G., & Bencivenni, G. (2011). An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid‐Catalysed Pictet–Spengler Reactions of Isatins. Advanced Synthesis & Catalysis. https://doi.org/10.1002/adsc.201100050

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