The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
The D‐dimer assay
Open accessAbstract
D‐dimer is an indirect marker of fibrinolysis and fibrin turnover; this molecule exhibits unique properties as a biological marker of hemostatic abnormalities as well as an indicator of intravascular thrombosis. D‐dimer is a soluble fibrin degradation product that results from the systematic degradation of vascular thrombi through the fibrinolytic mechanism. Because of this, the D‐dimer serves as a valuable marker of activation of coagulation and fibrinolysis in a number of clinical scenarios. Most commonly, D‐dimer has been extensively investigated for excluding the diagnosis of venous thromboembolism (VTE) and is used routinely for this indication. In addition, D‐dimer has been evaluated for determining the optimal duration of anticoagulation in VTE patients, for diagnosing and monitoring disseminated intravascular coagulation, and for monitoring other conditions in which the patient is at high risk of bleeding or thrombosis. Limitations of the assay include D‐dimer elevation in a constellation of clinical scenarios (age, pregnancy, and cancer) and lack of clinical standardization.
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Taylor, F., Toh, C.-H., Hoots, K., Wada, H., & Levi, M. (2001) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1616068 · Cited by 2,285
Evaluation of D-Dimer in the Diagnosis of Suspected Deep-Vein Thrombosis
Wells, P. S., Anderson, D. R., Rodger, M., Forgie, M., Kearon, C., Dreyer, J., Kovacs, G., Mitchell, M., Lewandowski, B., & Kovacs, M. J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa023153 · Cited by 1,552
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study
Righini, M., Van Es, J., Den Exter, P. L., Roy, P.-M., Verschuren, F., Ghuysen, A., Rutschmann, O. T., Sanchez, O., Jaffrelot, M., Trinh-Duc, A., et al. (2014) · JAMA · doi:10.1001/jama.2014.2135 · Cited by 958
D-dimer antigen: current concepts and future prospects
Adam, S. S., Key, N. S., & Greenberg, C. S. (2009) · Blood · doi:10.1182/blood-2008-06-165845 · Cited by 668
d -Dimer Testing to Determine the Duration of Anticoagulation Therapy
Palareti, G., Cosmi, B., Legnani, C., Tosetto, A., Brusi, C., Iorio, A., Pengo, V., Ghirarduzzi, A., Pattacini, C., Testa, S., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054444 · Cited by 622
Diagnostic accuracy of D‐dimer test for exclusion of venous thromboembolism: a systematic review
DI NISIO, M., SQUIZZATO, A., RUTJES, A. W. S., BÜLLER, H. R., ZWINDERMAN, A. H., & BOSSUYT, P. M. M. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02328.x · Cited by 465
TOH, C. H., & HOOTS, W. K. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02313.x · Cited by 381
Raja, A. S., Greenberg, J. O., Qaseem, A., Denberg, T. D., Fitterman, N., Schuur, J. D., & for the Clinical Guidelines Committee of the American College of Physicians* (2015) · Annals of Internal Medicine · doi:10.7326/m14-1772 · Cited by 340
Wada, H., Matsumoto, T., & Yamashita, Y. (2014) · Journal of Intensive Care · doi:10.1186/2052-0492-2-15 · Cited by 325
Palareti, G., Legnani, C., Cosmi, B., Valdré, L., Lunghi, B., Bernardi, F., & Coccheri, S. (2003) · Circulation · doi:10.1161/01.cir.0000079162.69615.0f · Cited by 276
Metadata
- Authors
- Johnson, E. D., Schell, J. C., & Rodgers, G. M.
- Venue
- American Journal of Hematology
- Publisher
- Wiley
- Published
- 2019-04-19
- Volume
- 94
- Issue
- 7
- Pages
- 833-839
- ISSN
- 0361-8609 (ISSN-L)
- 1096-8652
- OpenAlex
- W2929726298
- Cited by
- 303
- References
- 32
- FWCI
- 12.69
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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