A novel AXIN2 gene mutation in sagittal synostosis

The bones of the skull are held together by fibrous joints called sutures. Premature fusion of these sutures leads to a pathologic condition called as craniosynostosis. Although at least 50 nuclear genes including FGFR2 , TWIST1 , TCF12 , and SMAD6 were identified as causative of craniosynostosis…