Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia
Open accessAbstract
Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTD) have provided evidence-based dementia guidelines for Canadian clinicians and researchers. We present the results of the 5th CCCDTD, which convened in October 2019, to address topics chosen by the steering committee to reflect advances in the field, and build on previous guidelines. Topics included: (1) utility of the National Institute on Aging research framework for clinical Alzheimer's disease (AD) diagnosis; (2) updating diagnostic criteria for vascular cognitive impairment, and its management; (3) dementia case finding and detection; (4) neuroimaging and fluid biomarkers in diagnosis; (5) use of non-cognitive markers of dementia for better dementia detection; (6) risk reduction/prevention; (7) psychosocial and non-pharmacological interventions; and (8) deprescription of medications used to treat dementia. We hope the guidelines are useful for clinicians, researchers, policy makers, and the lay public, to inform a current and evidence-based approach to dementia.
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Eight guidelines explicitly stated that they were prepared by, or in consultation with, people working in primary care.
“Eight guidelines explicitly stated that they were prepared by, or in consultation with, people working in primary care [36, 45–51].”
From Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework (2022) · cites this paper as [47]
Some guidelines targeted patients spanning midlife and late life, or across the life course.
“For age, some guidelines targeted patients spanning midlife and late life [37, 38, 49, 51, 52], or across the life course [45, 47].”
From Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework (2022) · cites this paper as [47]
Five guidelines recommended targeting DRR towards patients with one or more relevant risk factors.
“For risk factors, five guidelines recommended targeting DRR towards patients with one or more relevant risk factors [36, 47, 48, 50, 51].”
From Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework (2022) · cites this paper as [47]
Four guidelines were explicit about management that was not appropriate specifically for DRR, such as hormone replacement therapy, antidepressant medicines, or treatment of sleep disorders.
“Four guidelines were explicit about management that was not appropriate specifically for DRR, such as hormone replacement therapy [38, 52], antidepressant medicines [2], or treatment of sleep disorders [47].”
From Dementia Risk Reduction in Primary Care: A Scoping Review of Clinical Guidelines Using a Behavioral Specificity Framework (2022) · cites this paper as [47]
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References 134 · Cited by 245
Research works printed but not linked: 6
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- [8]Montero‐Odasso M, Almeida QJ, Bherer L, et al. Consensus on shared measures of mobility and cognition: from the Canadian Consortium on Neurodegeneration in Aging (CCNA). J Gerontol A Biol Sci Med Sci. 2018; 74: 897‐ 909. PMC6521916 30101279
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- [50]WHO. Risk reduction of cognitive decline and dementia: WHO guidelines. Geneva: World Health Orgaization; 2019. 31219687
- Authors
- Ismail, Z., Black, S. E., Camicioli, R., Chertkow, H., Herrmann, N., Laforce, R., Montero‐Odasso, M., Rockwood, K., Rosa‐Neto, P., Seitz, D., Sivananthan, S., Smith, E. E., Soucy, J., Vedel, I., Gauthier, S., & participants, T. C.
- Affiliations
- University of Calgary (CA)
- Sunnybrook Health Science Centre (CA)
- University of Alberta (CA)
- University of Toronto (CA)
- Université Laval (CA)
- Western University (CA)
- Dalhousie University (CA)
- McGill University Research Centre for Studies in Aging (CA)
- Alzheimer Society of Canada (CA)
- Montreal Neurological Institute and Hospital (CA)
- McGill University (CA)
- Corresponding author
- Gauthier, Serge
- ORCID
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2020-07-29
- Volume
- 16
- Issue
- 8
- Pages
- 1182-1195
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- PMC
- PMC7984031
- OpenAlex
- W3046195846
- Cited by
- 245
- References
- 134
- Citations by year
- 2026: 25 · 2025: 47 · 2024: 48 · 2023: 47 · 2022: 44 · 2021: 22 · 2020: 10 · 2017: 1 · 2012: 1
- FWCI
- 22.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Alzheimer s & Dementia (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- dementia diagnosis, dementia treatment
- MeSH terms
- Canada, Dementia, Humans
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