Machine learning prediction of tau‐PET in Alzheimer's disease using plasma, MRI, and clinical data

Karlsson, Linda; Vogel, Jacob; Arvidsson, Ida; Åström, Kalle; Strandberg, Olof; Seidlitz, Jakob; Bethlehem, Richard A. I.; Stomrud, Erik; Ossenkoppele, Rik; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Palmqvist, Sebastian; Smith, Ruben; Janelidze, Shorena; La Joie, Renaud; Rabinovici, Gil D.; Binette, Alexa Pichet; Mattsson‐Carlgren, Niklas; Hansson, Oskar

doi:10.1002/alz.14600

Machine learning prediction of tau‐PET in Alzheimer's disease using plasma, MRI, and clinical data

INTRODUCTION Tau positron emission tomography (PET) is a reliable neuroimaging technique for assessing regional load of tau pathology in the brain, but its routine clinical use is limited by cost and accessibility barriers. METHODS We thoroughly investigated the ability of various machine learnin…