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2025 Alzheimer's disease facts and figures
Open accessAbstract
This article describes the public health impact of Alzheimer's disease (AD), including prevalence and incidence, mortality and morbidity, use and costs of care, and the ramifications of AD for family caregivers, the dementia workforce, and society. The Special Report discusses Americans’ attitudes about early diagnosis and treatment of AD. An estimated 7.2 million Americans age 65 and older live with Alzheimer's dementia today. This number could grow to 13.8 million by 2060, barring the development of medical breakthroughs to prevent or cure AD. Official AD death certificates recorded 120,122 deaths from AD in 2022. Since 2020, when COVID‐19 became one of the top 10 causes of death in the United States, AD has ranked as the seventh‐leading cause of death. However, 2023 data indicate that Alzheimer's will likely resume its place as the sixth‐leading cause of death. Between 2000 and 2022, deaths from stroke, heart disease, and HIV decreased, whereas reported deaths from AD increased by more than 142%. Nearly 12 million family members and other unpaid caregivers provided an estimated 19.2 billion hours of care to people with Alzheimer's or other dementias in 2024. These figures reflect a decline in the number of caregivers compared with a decade earlier and an increase in the amount of care provided by each remaining caregiver. Unpaid dementia caregiving was valued at $413.5 billion in 2024. Its costs, however, extend to unpaid caregivers’ increased risk for emotional distress and negative mental and physical health outcomes. Members of the paid health care and broader community‐based workforce are involved in diagnosing, treating, and caring for people with dementia. However, the United States faces growing shortages across many segments of the dementia care workforce due to a combination of factors, including the absolute increase in the number of people living with dementia. Therefore, targeted programs and care delivery models are urgently needed to attract, better train, and effectively deploy health care and community‐based workers to provide dementia care. Average per‐person Medicare payments for services to beneficiaries age 65 and older with AD or other dementias are almost three times as great as payments for beneficiaries without these conditions, and Medicaid payments are more than 22 times as great. Total payments in 2025 for health care, long‐term care, and hospice services for people age 65 and older with dementia are estimated to be $384 billion. The Special Report examines Americans' thoughts about new developments in diagnosing and treating AD. Based on survey results, most Americans believe early detection of Alzheimer's is important, and nearly all would want a simple diagnostic test if it were available to allow for early diagnosis and treatment. About two‐thirds of Americans are aware that new medications exist to slow the progression of AD, and most feel optimistic about the future of new Alzheimer's treatments over the next decade.
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1 retracted
Leng, M., Zhao, Y., Xiao, H., Li, C., & Wang, Z. (2020) · Journal of Medical Internet Research · doi:10.2196/19468 · Cited by 183
RetractedMeyer, I. H. (2003) · Psychological Bulletin · doi:10.1037/0033-2909.129.5.674 · Cited by 14,736
ASSESSMENT OF COMA AND IMPAIRED CONSCIOUSNESS
Teasdale, G., & Jennett, B. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91639-0 · Cited by 13,215
Centers for Disease Control and Prevention
(2007) · Encyclopedia of Measurement and Statistics · doi:10.4135/9781412952644.n74 · Cited by 6,444
Lecanemab in early Alzheimer's disease
van Dyck, C. H., Swanson, C. J., Aisen, P., Bateman, R. J., Chen, C., Gee, M., Kanekiyo, M., Li, D., Reyderman, L., Cohen, S., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2212948 · Cited by 5,678
Structural racism and health inequities in the USA: evidence and interventions
Bailey, Z. D., Krieger, N., Agénor, M., Graves, J., Linos, N., & Bassett, M. T. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30569-x · Cited by 5,203
2016 Alzheimer's disease facts and figures
Alzheimer's Association (2016) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.03.001 · Cited by 5,069
Probst, C. O. (1910) · Journal of the American Medical Association · doi:10.1001/jama.1910.04330120065030 · Cited by 4,297
What is cognitive reserve? Theory and research application of the reserve concept
STERN, Y. (2002) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617702813248 · Cited by 3,951
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
Livingston, G., Huntley, J., Liu, K. Y., Costafreda, S. G., Selbæk, G., Alladi, S., Ames, D., Banerjee, S., Burns, A., Brayne, C., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01296-0 · Cited by 3,860
Research works printed but not linked: 45
- 10.1037/cns0000259 · doi:10.1037/cns0000259
- 10.1002/alz.13667 · doi:10.1002/alz.13667
- Institute of Medicine, 2015, Cognitive Aging: Progress in Understanding and Opportunity for Action
- Matthew J, 2024, Blood pressure, antihypertensive use, and late‐life Alzheimer and non‐Alzheimer dementia risk, Neurology, 103
- Jensen CS, 2019, Patients with Alzheimer's disease who carry the APOE e4 allele benefit more from physical exercise, TRCI, 5, 99
- Grodstein F, 2025, Late‐life social activity and subsequent risk of dementia and mild cognitive impairment, Alzheimers Dement
- Manly JJ, 2004, Critical perspectives on racial and ethnic differentials in health in late life, 95
- Cottrill A, 2024, Income and Assets of Medicare Beneficiaries in 2023
- Tejada‐Vera B, 2013, National Center for Health Statistics Data Brief, No. 116
- 10.1001/jama.2018.0158 · DOI
- Kasper JD, 2014, Disability and Care Needs of Older Americans by Dementia Status: An Analysis of the 2011 National Health and Aging Trends Study
- National Alliance for Caregiving in Partnership with the Alzheimer's Association
- 10.1111/jgs.19062 · doi:10.1111/jgs.19062
- Maslow K, 2012, Translating Innovation to Impact: Evidence‐Based Interventions to Support People with Alzheimer's Disease and their Caregiver at Home and in the Community
- 10.1037/pag0000696 · DOI · Paper page
- Gitlin LN, Dementia caregiver intervention research now and into the future: Review and recommendations
- Whitlatch CJ, 2018, Meeting the informational, educational, and psychosocial support needs of persons living with dementia and their family caregivers, Gerontologist, 58, S58
- Alzheimer's Association and Centers for Disease Control and Prevention, 2018, Healthy Brain Initiative, State and Local Public Health Partnerships to Address Dementia: The 2018‐2023 Road Map
- 10.1111/jgs.19143 · doi:10.1111/jgs.19143
- National Resident Matching Program, 2023, Results and Data: Specialties Matching Service
- Scales K, 2023, Direct care workers are the foundation of a dementia‐capable workforce, Generations, 47, 1
- PHI, 2024, Direct Care Workers in the United States: Key Facts
- Campbell S, 2021, Caring for the Future: The Power and Potential of America's Direct Care Workforce
- Donlan A, 2023, After 3‐Year Dip, Home Care Turnover Soars to 77%, Home Health Care News
- Weller C, Making Care Work Pay
- Khavjou O, Wages of direct care workers lower than other entry‐level jobs in most states (Issue brief)
- The White House.Fact sheet: The White House Conference on Aging. Accessed December 17 2024.https://obamawhitehouse.archives.gov/the‐press‐office/2015/07/13/fact‐sheet‐white‐house‐conference‐aging
- Cherry DL, 2012, HCBS can keep people with dementia at home, Generations, 36, 83
- Dickey TJ, 2023, How Public Libraries Build Sustainable Communities in the 21st Century (Advances in Librarianship, Vol. 53), 283
- Alzheimer's Association, 2024, Alzheimer's Disease Facts and Figures
- Ty D, 2021, Building Workforce Capacity to Improve Detection and Diagnosis of Dementia
- Alzheimer's Association, 2021, 2021 Alzheimer's Disease Facts and Figures. Special Report: Race, Ethnicity and Alzheimer's in America, Alzheimers Dement, 17, 377
- Winters A, 2021, State Strategies for Sector Growth and Retention for the Direct Care Health Workforce
- CairnsC KangK.National Hospital Ambulatory Medical Care Survey: 2020 emergency department summary tables. Accessed December 8 2024.https://dx.doi.org/10.15620/cdc:121911 · DOI · Paper page
- Sengupta M, 2022, Post‐acute and long‐term care providers and services users in the United States, 2017‐2018. National Center for Health Statistics, Vital Health Stat, 3, 1
- Murray C, 2023, Medicaid Long Term Services and Supports Annual Expenditures Report: Federal Fiscal Year 2020
- Bynum J, 2009, Characteristics, Costs, and Health Service Use for Medicare Beneficiaries with a Dementia Diagnosis: Report 1: Medicare Current Beneficiary Survey. Unpublished; provided under contract with the Alzheimer's Association
- Bynum JPW, 2016, A Report of the Dartmouth Atlas Project
- Lamont H, 2021, The Impact of COVID‐19 on Medicare Beneficiaries with Dementia (Issue Brief)
- Cubanski J, 2024, FAQs on Medicare Financing and Trust Fund Solvency
- Alzheimer's Association, 2022, 2022 Alzheimer's Disease Facts and Figures, Special Report: More Than Normal Aging: Understanding Mild Cognitive Impairment, Alzheimers Dement, 18, 754
- 10.1093/jlb/lsab004 · doi:10.1093/jlb/lsab004
- Schünemann HJ, 2024, Cochrane Handbook for Systematic Reviews of Interventions version 6.5
- Alzheimer's Association, 2020, 2020 Alzheimer's Disease Facts and Figures. Special Report: On the Front Lines: Primary Care Physicians and Alzheimer's Care in America, Alzheimers Dement, 16, 433
- Alzheimer's Association, 2023, 2023 Alzheimer's Disease Facts and Figures. Special Report: The Patient Journey In an Era of New Treatments, Alzheimers Dement, 19, 1656
Cited by
Rodriguez Martinez, P. J., Yslas, A. R., Inoue, Y., Parsons, T. M., Baker, S. K., Lu, W., Raulin, A.-C., & Kanekiyo, T. (2026) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2026.1778856
Metadata
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2025-04
- Volume
- 21
- Issue
- 4
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- OpenAlex
- W4409980681
- Cited by
- 474
- References
- 888
- FWCI
- 289.49
- Type
- journal article
- Language
- en
- Open access
- hybrid
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