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Cited by 493

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Continuous growth of mean tumor diameter in a subset of grade II gliomas

Mandonnet, Emmanuel, Delattre, Jean‐Yves, Tanguy, Marie‐Laure, Swanson, Kristin R., Carpentier, Antoine F., Duffau, Hugues, Cornu, Philippe, Van Effenterre, Rémy, Alvord, Ellsworth C., Capelle, Laurent·2003·Annals of Neurology

Abstract

Serial magnetic resonance images of 27 patients with untreated World Health Organization grade II oligodendrogliomas or mixed gliomas were reviewed retrospectively to study the kinetics of tumor growth before anaplastic transformation. Analysis of the mean tumor diameters over time showed constant growth. Linear regression, using a mixed model, found an average slope of 4.1mm per year (95% confidence interval, 3.8–4.4mm/year). Untreated low‐grade oligodendrogliomas or mixed gliomas grow continuously during their premalignant phase, and their pattern of growth can be predicted within a relatively narrow range. These findings could be of interest to optimize patients management and follow‐up. Ann Neurol 2003;53:524–528

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Metadata

Authors
Mandonnet, E., Delattre, J., Tanguy, M., Swanson, K. R., Carpentier, A. F., Duffau, H., Cornu, P., Van Effenterre, R., Alvord, E. C., & Capelle, L.
Venue
Annals of Neurology
Publisher
Wiley
Published
2003-03-24
Volume
53
Issue
4
Pages
524-528
ISSN
  • 0364-5134 (ISSN-L)
  • 1531-8249
OpenAlex
W1981472502
Cited by
493
References
0
FWCI
4.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Continuous growth of mean tumor diameter in a subset of grade II gliomas. https://app.cochat.ai/papers/10.1002/ana.10528
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Mandonnet, E., Delattre, J., Tanguy, M., Swanson, K. R., Carpentier, A. F., Duffau, H., Cornu, P., Van Effenterre, R., Alvord, E. C., & Capelle, L. (2003). Continuous growth of mean tumor diameter in a subset of grade II gliomas. Annals of Neurology. https://doi.org/10.1002/ana.10528

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