Gut Microbial Ecosystem in Parkinson Disease: New Clinicobiological Insights from Multi‐Omics
Tan, Ai Huey, Chong, Chun Wie, Lim, Shen‐Yang, Yap, Ivan Kok Seng, Teh, Cindy Shuan Ju, Loke, Mun Fai, Song, Sze‐Looi, Tan, Jiun Yan, Ang, Ban Hong, Tan, Yong Qi, Kho, Mee Teck, Bowman, Jeff, Mahadeva, Sanjiv, Yong, Hoi Sen, Lang, Anthony E.·2021·Annals of Neurology
Cited by (196)
Items 101–196 of 196
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- Gut microbiota and inflammation in Parkinson’s disease: Pathogenetic and therapeutic insightsTong Guo, Li Chen · 2022 · European Journal of Inflammation
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- Administering Lactiplantibacillus fermentum F6 decreases intestinal Akkermansia muciniphila in a dextran sulfate sodium-induced rat colitis modelQiuwen He, Tao Zhang, Weiqin Zhang, Cuijiao Feng, Lai‐Yu Kwok, Heping Zhang, Zhihong Sun · 2024 · Food & Function
- The Intricate Interplay: Microbial Metabolites and the Gut‐Liver‐Brain Axis in Parkinson's DiseaseDayamrita Kollaparampil Kishanchand, Athira Krishnan K. A., Krishnapriya Chandrababu, Cyriac Abby Philips, Unnikrishnan Sivan, P. S. Baby Chakrapani · 2025 · Journal of Neuroscience Research
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- Inflammatory gut as a pathologic and therapeutic target in Parkinson’s diseaseJea-Young Lee, Zhen-Jie Wang, Alexa Moscatello, Chase Kingsbury, Blaise Cozene, Jeffrey Farooq, Madeline Saft, Nadia Sadanandan, Bella Gonzales‐Portillo, Henry Zhang et al. · 2022 · Cell Death Discovery
- Oral and gut microbiome profiles in people with early idiopathic Parkinson’s diseaseKeaton Stagaman, Matthew J. Kmiecik, Madeleine Wetzel, Stella W. Aslibekyan, Teresa Filshtein Sönmez, Pierre Fontanillas, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg et al. · 2024 · Communications Medicine
- Imaging flow cytometry reveals LPS-induced changes to intracellular intensity and distribution of α-synuclein in a TLR4-dependent manner in STC-1 cellsAnastazja M. Gorecki, Chidozie C. Anyaegbu, Melinda Fitzgerald, Kathryn A. Fuller, Ryan S. Anderton · 2024 · Methods
- Probing the diagnostic values of plasma cf-nDNA and cf-mtDNA for Parkinson’s disease and multiple system atrophyYing Chao, Yuan Li, Hui Zhang, Shimin Pang, Shuwen Hao, Songnian Hu, Lifang Zhao · 2024 · Frontiers in Neuroscience
- Specific Bacterial Taxa and Their Metabolite, DHPS, May Be Linked to Gut Dyshomeostasis in Patients with Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral SclerosisCourtney Jayde Christopher, Katherine Hope Morgan, Christopher Tolleson, Randall Trudell, Roberto Fernandez-Romero, Leanne Rice, Blessing A Abiodun, Zane A. Vickery, Katarina A. Jones, Brittni Woodall et al. · 2025 · Nutrients
- Fecal Microbiota Transplantation for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsMuhammad Hassan Waseem, Zain Ul Abideen, Areeba Shoaib, Nohela Rehman, Muhammad Osama, Barka Sajid, Rowaid Ahmad, Zara Fahim, Muhammad Ahsan Ansari, Sania Aimen et al. · 2025 · Journal of Central Nervous System Disease
- Detection of Volatile Organic Compounds as an emerging strategy for Parkinson’s disease diagnosis and monitoringIlaria Belluomo, Munir Tarazi, Nicholas P Lao–Kaim, Yen Tai, Patrik Španěl, George Bushra Hanna · 2025 · npj Parkinson s Disease
- Advice to People with Parkinson’s in My Clinic: Probiotics and PrebioticsJia Wei Hor, Tzi Shin Toh, Shen‐Yang Lim, Ai Huey Tan · 2024 · Journal of Parkinson s Disease
- Stem Cells for Aging-Related DisordersMia C. Borlongan, Jeffrey Farooq, Nadia Sadanandan, Zhen-Jie Wang, Blaise Cozene, Jea-Young Lee, Gary Kenneth Steinberg · 2021 · Stem Cell Reviews and Reports
- Intestinal microbiota distribution and changes in different stages of Parkinson's disease: A meta-analysis, bioinformatics analysis and in vivo simulationTingyue Jiang, Yu Wang, Wenxin Fan, Yifan Lu, Ge Zhang, Jiayuan Li, Rui Ma, Mengmeng Liu, Jinli Shi · 2025 · BioScience Trends
- The Enteric Nervous System as a Mediator of Microbiota‐Gut‐Brain Interactions in Parkinson's DiseaseLuisa Valdetaro, Maria Carolina Ricciardi, P. G Almeida, Milena Barcza Stockler‐Pinto, Ana Lúcia Tavares Gomes · 2026 · Journal of Neurochemistry
- Association between major dietary patterns and Parkinson’s disease risk: a case–control studyNafiseh Shokri Mashhadi, Reza Ghiasvand, Awat Feizi, Mohsen Ebrahimi-Monfared, Farhad Vahid, Akram Banijamali · 2023 · Neurological Sciences
- Crosstalk between gut microbiome and neuroinflammation in pathogenesis of HIV-associated neurocognitive disorderXue Chen, Jiaqi Wei, Yang Zhang, Yulin Zhang, Tong Zhang · 2024 · Journal of the Neurological Sciences
- NEMoE: a nutrition aware regularized mixture of experts model to identify heterogeneous diet-microbiome-host health interactionsXiangnan Xu, Michal Lubomski, Andrew J. Holmes, Carolyn M. Sue, Ryan L. Davis, Samuel Müller, Jean Yee Hwa Yang · 2023 · Microbiome
- Alterations of Gut Microbiota and Microbial Metabolites in Parkinson’s Disease: A Systematic ReviewSamin Davoody, Kimia Ghazi Vakili, Kimia Jazi, Mobina Fathi, Mahsa Heidari‐Foroozan, Seyed Ali Mofidi, Mahsa Taremi, Amirreza Taherkhani, Sina Azadnajafabad, Fatemeh Hojjatipour et al. · 2025 · Molecular Neurobiology
- Gastric microbiota and its role in gastric carcinogenesisXiaowen Jiang, Lei Peng, Li Zhang, Zhexuan Li, Tong Zhou, Jingying Zhang, Wenqing Li, Wei‐Cheng You, Yang Zhang, Kai‐Feng Pan · 2023 · Malignancy Spectrum
- Deciphering the microbial map and its implications in the therapeutics of neurodegenerative disorderShrutikirti Vashishth, Rashmi K. Ambasta, Pravir Kumar · 2024 · Ageing Research Reviews
- The role of gut-derived short-chain fatty acids in Parkinson's diseaseMohamed Jamal Saadh, Anfal Nabeel Mustafa, Mohammed Ahmed Mustafa, Renuka Jyothi S, Hasan Khalid Dabis, G. V. Siva Prasad, Imad Jassim Mohammad, Ahmed Adnan, Ameer Hassan Idan · 2024 · Neurogenetics
- Limitations and opportunities in multi-omics integration for neurodevelopmental, neurodegenerative and psychiatric disorders: A systematic reviewLuiza Marques Prates Behrens, Guilherme da Silva Fernandes, Gabriela Flores Gonçalves, Franklin Vinny Medina Nunes, Rafael Diogo Weimer, José Cláudio Fonseca Moreira, Márcio Dorn · 2026 · Neuroscience
- Disease modifying therapies for Parkinson's disease: Novel targetsNirosen Vijiaratnam, Thomas Foltynie · 2021 · Neuropharmacology
- Glycolipids in Parkinson's disease: beyond neuronal functionFokion Spanos, Michela Deleidi · 2023 · FEBS Open Bio
- Recent Trends in Metabolomics by NMR SpectroscopyGiorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat · 2026 · Angewandte Chemie International Edition
- Metabolic Disturbances in the Gut-brain Axis of a Mouse Model of MPTP-induced Parkinsonism Evaluated by Nuclear Magnetic ResonanceDionísio Pedro Amorim Neto, João Vitor Pereira de Godoy, Katiane Tostes, Beatriz Pelegrini Bosque, Paulla Vieira Rodrigues, Silvana A. Rocco, Mauricio Luis Sforça, Matheus de Castro Fonseca · 2023 · Neuroscience
- Neurophysiology of Brain Networks Underlies Symptoms of Parkinson’s Disease: A Basis for Diagnosis and ManagementMartha Teresa Acosta-Mejia, Nelson Villalobos · 2023 · Diagnostics
- Plasma trimethylamine N-oxide, carnitine, choline, and betaine distinguish cognition impairment in Parkinson's diseaseZhaohan Xu, Hucheng Chen, Guoyan Zheng, Wei Zhang, Jing Wang, Jian Zhang, Qing Gao, Jun Wu, Xue Xue · 2025 · Parkinsonism & Related Disorders
- The influence of aging and the microbiome in multiple sclerosis and other neurologic diseasesNaomi M. Fettig, Annie Pu, Lisa C. Osborne, Jennifer L. Gommerman · 2024 · Immunological Reviews
- Parkinson’s Disease Through the Lens of Metabolomics: A Targeted Systematic Review on Human Studies (2019–2024)Federico Cannas, Karolina Krystyna Kopeć, Natalia Zuddas, Flaminia Cesare Marincola, Giorgio Arcara, Michele Loi, Michele Mussap, Vassilios Fanos · 2025 · Journal of Clinical Medicine
- Causal relationship between gut microbiota, lipids, and neuropsychiatric disorders: A Mendelian randomization mediation studyNan Zhang, Xiaoyu Dong · 2025 · Journal of Affective Disorders
- Intestinal biomarkers, microbiota composition, and genetic predisposition to inflammatory bowel disease as predictors of Parkinson's disease manifestationZhi Chai, Yuxia Ouyang, Anketse Debebe, Mellissa Picker, Wonjun Lee, Seth Fenton, Anouck Becker, Kerstin Augustin-Emmerichs, Andreas Schwiertz, Susanne Nicole Weber et al. · 2025 · Journal of Parkinson s Disease
- Unraveling the Relation of Parkinson's Disease and Metabolites: A Combined Analysis of Stool and Plasma Metabolites Based on Untargeted Metabolomics TechnologySufang Liu, Qiang Zhao, Jie Tang, Xianhong Li, Juan Wang, Yuting Zhao, Zhengting Yang, Xin Pan, Rui Hua Xiang, Jing Tian et al. · 2025 · CNS Neuroscience & Therapeutics
- Mitochondrial Dysfunction in Parkinson’s Disease: Is Impaired Deuterium Depleted Nutrient Supply by Gut Microbes a Primary Factor?Stephanie Seneff, Greg Nigh, Anthony M. Kyriakopoulos · 2025 · Biocell
- The Small Intestinal Microbiota and the Gut–Brain Axis in Parkinson’s Disease: A Narrative ReviewGloria Carrossa, Valentina Misenti, Sofia Faggin, Maria Cecilia Giron, Angelo Antonini · 2025 · Biomedicines
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- Parkinson’s disease beyond the brain: implications for treatmentsSetareh Malekian Naeini, Marc Danzell Lopez, Paul E. Fraser, Anurag Tandon · 2025 · Frontiers in Aging Neuroscience
- When Gut Hormones Influence Brain Function in DepressionI.P. Siba, Bruno Jacson Martynhak, Marcela Pereira · 2023 · Applied Biosciences
- The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine CellsAnastazja M. Gorecki, Holly L. Spencer, Bruno P. Meloni, Ryan S. Anderton · 2023 · Biomedicines
- Secondary analysis reveals gut microbiota differences in patients with Parkinson’s disease and/or cognitive impairmentXin Shen, Bing Leng, Shukun Zhang, Lai‐Yu Kwok, Feiyan Zhao, Jia Zhao, Zhihong Sun, Jinbiao Zhang · 2024 · Microbiome Research Reports
- Development and validation of nomogram for predicting cognitive frailty with multimorbidity: a cross-sectional studyChunbo Guo, Shunyin Liu, Yuehua Liu, Mengxi Zhang, Shan Liu, Liting Zeng, Luo Lu · 2025 · Frontiers in Public Health
- Nanotherapeutic Interventions for Parkinson’s Disease: Modulating Pathogenic Mechanisms and Overcoming Therapeutic ObstaclesXuanying Yin, Chen Wang, Weisen Lin, Shuiqing Huang, Tongkai Chen · 2026 · International Journal of Nanomedicine
- The neurobiology of fatty acids: Metabolism, signaling, and roles in neurodegenerative diseasesRocío Rojas, Alicia Pellitero, Betül Arslan, Alberto Pérez‐Samartín, Carlos Matute · 2026 · Progress in Lipid Research
- Improved Key Microbial Biomarker Discovery Using Ensemble Statistical MethodsWalter Pirovano, Yashjit Gangopadhyay, Mirna Lilian Baak, Christiaan de Leeuw, Radhika Bongoni, Eline Suzanne Klaassens · 2025 · Advanced Gut & Microbiome Research
- Immune and metabolic signatures characterise constipation-driven endophenotypes in Parkinson’s diseaseAbbey Figliomeni, Samantha J. Winter, Maddison Y. Abonnel, Jade E. Kenna, Samantha Lodge, Luke Whiley, Andrés Bernal, Jérôme D. Coudert, Jonathan Edward Noonan, Belinda J. Kaskow et al. · 2025 · npj Parkinson s Disease
- Gut bacteria composition in animal models of Parkinson’s disease: a systematic review and meta-analysisJoshua D. Elford, Elise Jasmijn Heesbeen, Nienke A. van der Plaats, Johan Garssen, Aletta D. Kraneveld, Lucianne Groenink, Paula Perez‐Pardo · 2026 · npj Parkinson s Disease
- Gut ecosystem dysfunction in parkinson’s disease: deciphering faecal metabolome-metagenome links for novel diagnostic panelsYiwei Qian, Shaoqing Xu, Xiaoqin He, Yiqiu Lai, Yi Zhang, Chengjun Mo, Penghui Ai, Xiaodong Yang, Qin Xiao · 2026 · npj Parkinson s Disease
- The Gut-Brain Axis: A Critical Link between Type 2 Diabetes and Parkinson’s diseaseNajlaa H. Almohmadi, Hayder M. Al‐kuraishy, Khulood S. Hussein, Arwa Turkistani, Fatimah M. Yousef, Ali Ismail Al-Gareeb, Ahmed M Abdelaziz, Yaser Hosny Ali Elewa, Gaber El‐Saber Batiha · 2026 · Probiotics and Antimicrobial Proteins
- Optimizing participant recruitment and retention in clinical studies by hearing the voices of persons with Parkinson'sXiao Yue Goh, Cholpon Shambetova, Tzi Shin Toh, Eliza Zhunusova, Yi Wen Tay, Jun Ping Chua, Winn Hui Han, Joanne Yu Li Lim, Ai Huey Tan, Shen‐Yang Lim · 2026 · Journal of Parkinson s Disease
- Immunology and microbiome: Implications for motor systemsYasamin Mahjoub, Davide Martino · 2023 · Handbook of clinical neurology
- Identification of metabolites reproducibly associated with Parkinson’s Disease via meta-analysis and computational modellingRonan M. T. Fleming, Xi Luo, Yanjun Liu, Alexander Balck, Christine Klein · 2023 · Research Square
- Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s diseaseStefano Romano, Jakob Wirbel, Rebecca Ansorge, Christian Schudoma, Quinten R. Ducarmon, Arjan Narbad, Georg Zeller · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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