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Cited by 247

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Pathology of the Guillain-Barr� syndrome

Prineas, J. W.·1981·Annals of Neurology

Abstract

The Guillain-Barré syndrome is a distinctive neuropathy characterized pathologically by the presence of inflammatory lesions which occur scattered throughout the peripheral nervous system. The lesions consist of circumscribed areas in which myelin is lost in the presence of lymphocytes and macrophages. Myelin damage of effected largely by macrophages, which penetrate the basement membrane around nerve fibers and strip what appears to be normal myelin away from the body of the Schwann cell and off the axon. While there is evidence that this activity is immune mediated, the precise mechanism that leads macrophages to seek out and amputate a specialized region of the Schwann cell plasma membrane remains unexplained.

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Metadata

Authors
Prineas, J. W.
Venue
Annals of Neurology
Publisher
Wiley
Published
1981
Volume
9
Issue
S1
Pages
6-19
ISSN
  • 0364-5134 (ISSN-L)
  • 1531-8249
OpenAlex
W2139039297
Cited by
247
References
1
FWCI
8.75
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Pathology of the Guillain-Barr� syndrome. https://app.cochat.ai/papers/10.1002/ana.410090704
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Prineas, J. W. (1981). Pathology of the Guillain-Barr� syndrome. Annals of Neurology. https://doi.org/10.1002/ana.410090704

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