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Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference

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Foster, Norman L., Wilhelmsen, Kirk, Sima, Anders A. F., Jones, Margaret Z., D'Amato, Constance J., Gilman, Sid, Conference Participants·1997·Annals of Neurology

Abstract

We held an international consensus conference on frontotemporal dementia, behavioral disturbances, and parkinsonism linked to chromosome 17 to determine whether these are homogeneous or heterogeneous disorders, to agree on terminology, and to develop strategies for further research. The group identified 13 kindreds with sufficient evidence for linkage, finding in common to all a critical 2 cM between markers D17S791 and D17S800. There was agreement that (1) despite previous descriptions that have emphasized one or another clinical or neuropathological feature, the kindreds share clinical and neuropathological features; (2) until more specific information about the genetic defects becomes available, this disorder is best termed frontotemporal dementia and parkinsonism linked to chromosome 17; and (3) further research will be enhanced by identifying the gene responsible for this disorder, detecting additional cases within known families and, in new families, correlating mutations with phenotypes and more fully delineating the clinical, neuropsychological, and neuropathological characteristics of this disorder.

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Metadata

Authors
Foster, N. L., Wilhelmsen, K., Sima, A. A. F., Jones, M. Z., D'Amato, C. J., Gilman, S., & Participants, C.
Venue
Annals of Neurology
Publisher
Wiley
Published
1997-06
Volume
41
Issue
6
Pages
706-715
ISSN
  • 0364-5134 (ISSN-L)
  • 1531-8249
OpenAlex
W1985131940
Cited by
634
References
0
FWCI
36.17
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference. https://app.cochat.ai/papers/10.1002/ana.410410606
The paper
Foster, N. L., Wilhelmsen, K., Sima, A. A. F., Jones, M. Z., D'Amato, C. J., Gilman, S., & Participants, C. (1997). Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference. Annals of Neurology. https://doi.org/10.1002/ana.410410606

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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