The DOI matches its Crossref record.
Which Factors Determine the Reactivity and Regioselectivity of Free Radical Substitution and Addition Reactions?
Abstract
The relative importance of bond strength, steric effects, and polarity in determining the rate and orientation of free radical subsitution and free radical addition reaction is considered. The factors which control substitution reaction (radical transfer reaction) are gathered together as five “rules”, and a similar five “rules” are proposed for addition rections. These “rules” are shown to be special cases of two “laws” which govern all free radical reactions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Proton-coupled electron transfer
Huynh, M. H. V., & Meyer, T. J. (2007) · Chemical Reviews · doi:10.1021/cr0500030 · Cited by 1,659
Photochemical Reactions as Key Steps in Organic Synthesis
Hoffmann, N. (2008) · Chemical Reviews · doi:10.1021/cr0680336 · Cited by 1,445
Understanding Hydrogen Atom Transfer: From Bond Strengths to Marcus Theory
Mayer, J. M. (2011) · Accounts of Chemical Research · doi:10.1021/ar100093z · Cited by 910
Fischer, H., & Radom, L. (2001) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20010417)40:8<1340::aid-anie1340>3.0.co;2-# · Cited by 709
Formation of Environmentally Persistent Free Radicals on Microplastics under Light Irradiation
Zhu, K., Jia, H., Zhao, S., Xia, T., Guo, X., Wang, T., & Zhu, L. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b01474 · Cited by 573
Metadata
- Authors
- Tedder, J. M.
- Venue
- Angewandte Chemie International Edition in English
- Publisher
- Wiley
- Published
- 1982-06
- Volume
- 21
- Issue
- 6
- Pages
- 401-410
- ISSN
- 0570-0833 (ISSN-L)
- OpenAlex
- W2081482983
- Cited by
- 402
- References
- 0
- FWCI
- 8.96
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Which Factors Determine the Reactivity and Regioselectivity of Free Radical Substitution and Addition Reactions? https://app.cochat.ai/papers/10.1002/anie.198204011
- The paper
- Tedder, J. M. (1982). Which Factors Determine the Reactivity and Regioselectivity of Free Radical Substitution and Addition Reactions? Angewandte Chemie International Edition in English. https://doi.org/10.1002/anie.198204011
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
