The DOI matches its Crossref record.
A DNA‐Based Machine That Can Cyclically Bind and Release Thrombin
Abstract
A DNA aptamer structure is the basis of a molecular machine that can be instructed to grab or release the human blood-clotting factor α-thrombin, depending on the operator DNA sequence addressing it. In the picture the aptamer structure, which assumes a conformation characterized by two stacked guanine quadruplex structures, is linked to thrombin (gray ellipse).
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Citations
Cited by
Principles and Applications of Nucleic Acid Strand Displacement Reactions
Simmel, F. C., Yurke, B., & Singh, H. R. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00580 · Cited by 792
Self-citationElectrochemistry of Nucleic Acids
Paleček, E., & Bartošík, M. (2012) · Chemical Reviews · doi:10.1021/cr200303p · Cited by 668
Synthetische molekulare Motoren und mechanische Maschinen
Kay, E. R., Leigh, D. A., & Zerbetto, F. (2007) · Angewandte Chemie · doi:10.1002/ange.200504313 · Cited by 624
DNA nanotechnology from the test tube to the cell
Chen, Y.-J., Groves, B., Muscat, R. A., & Seelig, G. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.195 · Cited by 594
Xiao, Y., Piorek, B. D., Plaxco, K. W., & Heeger, A. J. (2005) · Journal of the American Chemical Society · doi:10.1021/ja056555h · Cited by 527
Metadata
- Authors
- Dittmer, W. U., Reuter, A., & Simmel, F. C.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2004-06-29
- Volume
- 43
- Issue
- 27
- Pages
- 3550-3553
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2101175414
- Cited by
- 254
- References
- 0
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dittmer, W. U., Reuter, A., & Simmel, F. C. (2004). A DNA‐Based Machine That Can Cyclically Bind and Release Thrombin. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200353537
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
