The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Antibacterial and Hemolytic Activities of Pyridinium Polymers as a Function of the Spatial Relationship between the Positive Charge and the Pendant Alkyl Tail
Abstract
The benefits of separation: For homologous polymers having similar backbone composition and charge/tail ratios, placing the charge and alkyl tail on spatially separated centers results in a higher membrane-disrupting ability, as evident from the increased antibacterial and hemolytic activities. The spatial separation particularly amplifies mammalian cell toxicity (see picture).
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Cites
Polymeric coatings that inactivate both influenza virus and pathogenic bacteria
Haldar, J., An, D., Álvarez de Cienfuegos, L., Chen, J., & Klibanov, A. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608803103 · Cited by 297
Synergistic activity of hydrophilic modification in antibiotic polymers
Sellenet, P. H., Allison, B., Applegate, B. M., & Youngblood, J. P. (2007) · Biomacromolecules · doi:10.1021/bm0605513 · Cited by 130
Cited by
Polymeric materials with antimicrobial activity
Muñoz-Bonilla, A., & Fernández-García, M. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.08.005 · Cited by 1,221
Kuroda, K., Caputo, G. A., & DeGrado, W. F. (2009) · Chemistry – A European Journal · doi:10.1002/chem.200801523 · Cited by 346
Biomimetic antimicrobial polymers: recent advances in molecular design
Ergene, C., Yasuhara, K., & Palermo, E. F. (2018) · Polymer Chemistry · doi:10.1039/c8py00012c · Cited by 312
King, A., Chakrabarty, S., Zhang, W., Zeng, X., Ohman, D. E., Wood, L. F., Abraham, S., Rao, R., & Wynne, K. J. (2014) · Biomacromolecules · doi:10.1021/bm401794p · Cited by 72
Chakrabarty, S., King, A., Kurt, P., Zhang, W., Ohman, D. E., Wood, L. F., Lovelace, C., Rao, R., & Wynne, K. J. (2011) · Biomacromolecules · doi:10.1021/bm101381y · Cited by 37
Metadata
- Authors
- Sambhy, V., Peterson, B. R., & Sen, A.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2008-01-25
- Volume
- 47
- Issue
- 7
- Pages
- 1250-1254
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2131380952
- Cited by
- 271
- References
- 2
- FWCI
- 7.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sambhy, V., Peterson, B. R., & Sen, A. (2008). Antibacterial and Hemolytic Activities of Pyridinium Polymers as a Function of the Spatial Relationship between the Positive Charge and the Pendant Alkyl Tail. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200702287
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