Computed Tomography in Color: NanoK‐Enhanced Spectral CT Molecular Imaging
Open accessAbstract
Multicolored imaging: A new class of molecular imaging agent has been developed based on low-molecular-weight organically soluble bismuth to detect and quantify intraluminal fibrin presented by ruptured plaque in the context of computed tomography angiograms without calcium interference.
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Multicolour CT imaging was applied to visualize thrombi with fibrin-targeted bismuth nanocolloids in rabbit models of atherosclerosis.
“In a study by a different group, multicolour CT imaging was applied to visualize thrombi with fibrin-targeted bismuth nanocolloids in rabbit models of atherosclerosis143.”
From Perspectives and opportunities for nanomedicine in the management of atherosclerosis (2011) · cites this paper as [143]
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References 23 · Cited by 178
Research works printed but not linked: 1
- [23]a) Lanza GM Wallace KD Fischer SE Christy DH Scott MJ Miller JG Gaffney PJ Wickline SA J Acoust Soc Am 1997 10 391 b) Yu X Song SK Chen J Scott MJ Fuhrhop RJ Hall CS Gaffney PJ Wickline SA Lanza GM Magn Reson Med 2000 44 867 872 11108623
- Authors
- Pan, D., Roessl, E., Schlomka, J., Caruthers, S. D., Senpan, A., Scott, M. J., Allen, J. S., Zhang, H., Hu, G., Gaffney, P. J., Choi, E. T., Rasche, V., Wickline, S. A., Proksa, R., & Lanza, G. M.
- Affiliations
- Washington University in St. Louis (US)
- Philips (Germany) (DE)
- St Thomas' Hospital (GB)
- Universität Ulm (DE)
- Corresponding author
- Pan, Dipanjan
- Lanza, Gregory M.
- ORCID
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-11-12
- Volume
- 49
- Issue
- 50
- Pages
- 9635-9639
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- PMC
- PMC3096064
- OpenAlex
- W1997872530
- Cited by
- 178
- References
- 23
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 11 · 2023: 8 · 2022: 11 · 2021: 6 · 2020: 13 · 2019: 11 · 2018: 12 · 2017: 13 · 2016: 16 · 2015: 12 · 2014: 22 · 2013: 9 · 2012: 15
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Angewandte Chemie International Edition (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Public Health Service (R01L078631, U54A119342, R01L073646)
- National Heart, Lung, and Blood Institute (HL073646, R01HL073646)
- National Institute of Neurological Disorders and Stroke (R01NS059302)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced X-ray and CT Imaging
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiopharmaceutical Chemistry and Applications
- Keywords
- spectral CT, molecular imaging agents, CT angiography, calcium interference
- MeSH terms
- Animals, Bismuth, Colloids, Color, Contrast Media, Fibrin, Humans, Male, Mice, Inbred BALB C, Rabbits, Thrombosis, Tomography, X-Ray Computed, Mice, Nanoparticles
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