The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity
Abstract
Multicomponent reactions have become increasingly popular as tools for the rapid generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and complexity, there is a continuous need for novel reactions. Although serendipity has always played an important role in the discovery of novel (multicomponent) reactions, rational design strategies have become much more important over the past decade. In this Review, we present an overview of general strategies that allow the design of novel multicomponent reactions. The challenges and opportunities for the future will be discussed.
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Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00129-0 · Cited by 18,139
Cited by
Consecutive multicomponent reactions for the synthesis of complex molecules
Zhi, S., Ma, X., & Zhang, W. (2019) · Organic & Biomolecular Chemistry · doi:10.1039/c9ob00772e · Cited by 293
State-of-the-art strategies for targeting protein–protein interactions by small-molecule inhibitors
Sheng, C., Dong, G., Miao, Z., Zhang, W., & Wang, W. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00252d · Cited by 165
Metadata
- Authors
- Ruijter, E., Scheffelaar, R., & Orru, R. V. A.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2011-06-27
- Volume
- 50
- Issue
- 28
- Pages
- 6234-6246
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W1966922056
- Cited by
- 1,329
- References
- 1
- FWCI
- 47.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ruijter, E., Scheffelaar, R., & Orru, R. V. A. (2011). Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201006515
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