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Label‐Free Detection of Single‐Base Mismatches in DNA by Surface‐Enhanced Raman Spectroscopy
Open accessAbstract
Singles only: DNA sequences can be induced to spontaneously adsorb to the surfaces of Ag colloids through their nucleotide side chains (see picture). The SERS spectra of these nonspecifically bound strands are sufficiently reproducible that they can be used to identify single-base mismatches in short (25-mer and 23-mer) strands. Subtracting the spectra of different DNA sequences results in difference spectra that contain features corresponding to the exchanged nucleotides.
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Cited by
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Li, M., Cushing, S. K., & Wu, N. (2015) · The Analyst · doi:10.1039/c4an01079e · Cited by 1,011
SERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Tagging
Lane, L. A., Qian, X., & Nie, S. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00265 · Cited by 873
Multiplex in vitro detection using SERS
Laing, S., Gracie, K., & Faulds, K. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00644a · Cited by 361
Garcia-Rico, E., Alvarez-Puebla, R. A., & Guerrini, L. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00809k · Cited by 267
Kong, K. V., Lam, Z., Lau, W. K. O., Leong, W. K., & Olivo, M. (2013) · Journal of the American Chemical Society · doi:10.1021/ja409230g · Cited by 173
Metadata
- Authors
- Papadopoulou, E., & Bell, S. E. J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2011-07-19
- Volume
- 50
- Issue
- 39
- Pages
- 9058-9061
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W1976707311
- Cited by
- 193
- References
- 0
- FWCI
- 5.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Papadopoulou, E., & Bell, S. E. J. (2011). Label‐Free Detection of Single‐Base Mismatches in DNA by Surface‐Enhanced Raman Spectroscopy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201102776
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