The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper‐Free Click Reaction
Abstract
Built in for clicks: A specially evolved pyrrolysyl-tRNA synthetase from Methanosarcina mazei was used to incorporate a norbornene amino acid into proteins in E. coli. This unit can be site-selectively modified under mild physiological conditions using a [3+2] cycloaddition reaction with nitrile imines (see scheme).
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Citations
Cites
Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones
Jewett, J. C., Sletten, E. M., & Bertozzi, C. R. (2010) · Journal of the American Chemical Society · doi:10.1021/ja100014q · Cited by 697
Cited by
Bioorthogonal Reactions for Labeling Proteins
Lang, K., & Chin, J. W. (2014) · ACS Chemical Biology · doi:10.1021/cb4009292 · Cited by 555
Switchable Fluorophores for Single-Molecule Localization Microscopy
Li, H., & Vaughan, J. C. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00767 · Cited by 319
Labeling and Single-Molecule Methods To Monitor G Protein-Coupled Receptor Dynamics
Tian, H., Fürstenberg, A., & Huber, T. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00084 · Cited by 114
Metadata
- Authors
- Kaya, E., Vrabel, M., Deiml, C., Prill, S., Fluxa, V. S., & Carell, T.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2012-03-21
- Volume
- 51
- Issue
- 18
- Pages
- 4466-4469
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2146331709
- Cited by
- 163
- References
- 3
- FWCI
- 11.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper‐Free Click Reaction. https://app.cochat.ai/papers/10.1002/anie.201109252
- The paper
- Kaya, E., Vrabel, M., Deiml, C., Prill, S., Fluxa, V. S., & Carell, T. (2012). A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper‐Free Click Reaction. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201109252
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
