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Cited by 203

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Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light‐Responsive Tumor‐Targeting Molecule

Fan, Nien‐Chu, Cheng, Fong‐Yu, Ho, Ja‐an Annie, Yeh, Chen‐Sheng·2012·Angewandte Chemie International Edition
DOI 10.1002/anie.201203339
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Abstract

Light-controlled: Biodegradable nanoparticles encapsulating an anticancer drug (red dots in picture) have been synthesized that carry photocaged folate groups on the surface. Upon irradiation the photocaging group (green) is removed and the free folate group, a tumor-homing agent, binds to folate receptors on cell surfaces, thus leading to specific targeting and cellular uptake.

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Metadata

Authors
Fan, N., Cheng, F., Ho, J. A., & Yeh, C.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2012-07-25
Volume
51
Issue
35
Pages
8806-8810
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
DOI
10.1002/anie.201203339
OpenAlex
W2149556008
Cited by
203
References
0
FWCI
6.85
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light‐Responsive Tumor‐Targeting Molecule. https://app.cochat.ai/papers/10.1002/anie.201203339
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Fan, N., Cheng, F., Ho, J. A., & Yeh, C. (2012). Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light‐Responsive Tumor‐Targeting Molecule. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201203339

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.