The DOI matches its Crossref record; 231 of the 231 references it cites were found in a registry or an index.
Triplex DNA Nanostructures: From Basic Properties to Applications
Abstract
Triplex nucleic acids have recently attracted interest as part of the rich “toolbox” of structures used to develop DNA‐based nanostructures and materials. This Review addresses the use of DNA triplexes to assemble sensing platforms and molecular switches. Furthermore, the pH‐induced, switchable assembly and dissociation of triplex‐DNA‐bridged nanostructures are presented. Specifically, the aggregation/deaggregation of nanoparticles, the reversible oligomerization of origami tiles and DNA circles, and the use of triplex DNA structures as functional units for the assembly of pH‐responsive systems and materials are described. Examples include semiconductor‐loaded DNA‐stabilized microcapsules, DNA‐functionalized dye‐loaded metal–organic frameworks (MOFs), and the pH‐induced release of the loads. Furthermore, the design of stimuli‐responsive DNA‐based hydrogels undergoing reversible pH‐induced hydrogel‐to‐solution transitions using triplex nucleic acids is introduced, and the use of triplex DNA to assemble shape‐memory hydrogels is discussed. An outlook for possible future applications of triplex nucleic acids is also provided.
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Cited by
DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications
Dong, Y., Yao, C., Zhu, Y., Yang, L., Luo, D., & Yang, D. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00294 · Cited by 533
Metadata
- Authors
- Hu, Y., Cecconello, A., Idili, A., Ricci, F., & Willner, I.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2017-11-08
- Volume
- 56
- Issue
- 48
- Pages
- 15210-15233
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2609836588
- Cited by
- 336
- References
- 231
- FWCI
- 11.26
- Type
- journal article
- Language
- en
- Open access
- closed
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