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Normotensive renal failure in systemic sclerosis
Abstract
Of 140 patients with “scleroderma renal crisis” encountered during a 33‐year period, 15 of 131 (11%) whose blood pressures were recorded were normotensive during this complication. In comparison with 116 patients with hypertension, the normotensive patients significantly more often had microangiopathic hemolytic anemia (90% versus 38%) and thrombocytopenia (83% versus 21%). Pulmonary hemorrhage occurred in 6 normotensive patients. More normotensive patients had received high doses of corticosteroids (prednisone gE;30 mg/day) during the 2 months immediately preceding renal crisis (64% versus 16%). A role for corticosteroids in precipitating renal crisis is suggested. The 12‐month survival was significantly reduced in the normotensive patients (13% versus 35%).
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Cited by
Update of EULAR recommendations for the treatment of systemic sclerosis
Kowal-Bielecka, O., Fransen, J., Avouac, J., Becker, M., Kulak, A., Allanore, Y., Distler, O., Clements, P., Cutolo, M., Czirjak, L., et al. (2017) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2016-209909 · Cited by 1,104
Felson, D. T., Anderson, J. J., Lange, M. L. M., Wells, G., & LaValley, M. P. (1998) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199809)41:9 · Cited by 474
Steen, V. D., Costantino, J. P., Shapiro, A. P., & Medsger, T. A. (1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-5-352 · Cited by 441
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Metadata
- Authors
- Helfrich, D. J., Banner, B., Steen, V. D., & Medsger, T. A.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1989-09
- Volume
- 32
- Issue
- 9
- Pages
- 1128-1134
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W1984668559
- Cited by
- 217
- References
- 0
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- Helfrich, D. J., Banner, B., Steen, V. D., & Medsger, T. A. (1989). Normotensive renal failure in systemic sclerosis. Arthritis & Rheumatism. https://doi.org/10.1002/anr.1780320911
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