High frequency of fibromyalgia in patients with chronic fatigue seen in a primary care practice
Abstract
We administered a standardized history questionnaire and performed a tender point examination on 27 patients with debilitating fatigue of at least 6 months duration, seen in a primary care practice, as well as on 20 patients with fibromyalgia. Sixteen of the 27 patients with chronic fatigue met the full criteria for the working case definition of chronic fatigue syndrome (CFS). Eight patients with chronic fatigue denied having any current persistent, diffuse musculoskeletal pain, and their tender point scores were similar to those in 10 normal control subjects. In contrast, 19 patients with chronic fatigue (70%) had persistent, diffuse musculoskeletal pain. The results of their tender point examinations were similar to those of the patients with fibromyalgia. Thus, the majority of these patients with debilitating chronic fatigue, including those who met criteria for CFS, met the historical and tender point diagnostic criteria for fibromyalgia. The presence of current musculoskeletal pain will identify those CFS patients who have fibromyalgia.
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Studies of IBS among patients with chronic fatigue syndrome have reported a prevalence ranging from 35-92%.
“Studies of IBS among patients with chronic fatigue syndrome have reported a prevalence ranging from 35-92%.”
From Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes (2010) · cites this paper as [34]
35-70% of patients with CFS have FMS.
“Up to 70% of FMS patients have CFS33 and 35-70% of patients with CFS have FMS.33,34”
From Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes (2010) · cites this paper as [34]
Studies of IBS among CFS patients have reported a prevalence ranging from 35-92% with a median of 51%.
“Studies of IBS among CFS patients have reported a prevalence ranging from 35-92%34-38 with a median of 51%.4”
From Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes (2010) · cites this paper as [34]
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References 15 · Cited by 288
- Authors
- Goldenberg, D. L., Simms, R. W., Geiger, A., & Komaroff, A. L.
- Affiliations
- Boston University (US)
- Corresponding author
- Goldenberg, Don L.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1990-03
- Volume
- 33
- Issue
- 3
- Pages
- 381-387
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W2057351471
- Cited by
- 288
- References
- 15
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2017: 1 · 2016: 7 · 2015: 5 · 2014: 6 · 2013: 12 · 2012: 12
- FWCI
- 11.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Arthritis & Rheumatism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01ai027314-03)
- National Institute of Allergy and Infectious Diseases (1R00-AI-26788, 1R01AI27314)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- fibromyalgia, chronic fatigue syndrome, chronic fatigue, musculoskeletal pain, diagnostic criteria, primary care patients, diffuse pain
- MeSH terms
- Adult, Bone and Bones, Evaluation Studies as Topic, Female, Fibromyalgia, Humans, Middle Aged, Muscles, Physical Examination, Primary Health Care, Fatigue Syndrome, Chronic
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