A double‐blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder

Arnold, Lesley M.; Lu, Yili; Crofford, Leslie J.; Wohlreich, Madelaine; Detke, Michael J.; Iyengar, Smriti; Goldstein, David J.

doi:10.1002/art.20485

A double‐blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder

Objective To assess the efficacy and safety of duloxetine, a serotonin and norepinephrine reuptake inhibitor, in subjects with primary fibromyalgia, with or without current major depressive disorder. Methods This study was a randomized, double‐blind, placebo‐controlled trial conducted in 18 outpa…