The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Sex determination: insights from the chicken
Abstract
Not all vertebrates share the familiar system of XX:XY sex determination seen in mammals. In the chicken and other birds, sex is determined by a ZZ:ZW sex chromosome system. Gonadal development in the chicken has provided insights into the molecular genetics of vertebrate sex determination and how it has evolved. Such comparative studies show that vertebrate sex‐determining pathways comprise both conserved and divergent elements. The chicken embryo resembles lower vertebrates in that estrogens play a central role in gonadal sex differentiation. However, several genes shown to be critical for mammalian sex determination are also expressed in the chicken, but their expression patterns differ, indicating functional plasticity. While the genetic trigger for sex determination in birds remains unknown, some promising candidate genes have recently emerged. The Z‐linked gene, DMRT1, supports the Z‐dosage model of avian sex determination. Two novel W‐linked genes, ASW and FET1, represent candidate female determinants. BioEssays 26:120–132, 2004. © 2004 Wiley Periodicals, Inc.
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Luo, X., Ikeda, Y., & Parker, K. L. (1994) · Cell · doi:10.1016/0092-8674(94)90211-9 · Cited by 1,631
Steroid deficiency syndromes in mice with targeted disruption of Cyp11a1
Hu, M.-C., Hsu, N.-C., El Hadj, N. B., Pai, C.-I., Chu, H.-P., Wang, C.-K. L., & Chung, B.-C. (2002) · Molecular Endocrinology · doi:10.1210/me.2002-0055 · Cited by 153
Cited by
Ijiri, S., Kaneko, H., Kobayashi, T., Wang, D.-S., Sakai, F., Paul-Prasanth, B., Nakamura, M., & Nagahama, Y. (2008) · Biology of Reproduction · doi:10.1095/biolreprod.107.064246 · Cited by 411
Sex chromosomes and brain gender
Arnold, A. P. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1494 · Cited by 368
Sex determination, gonadal sex differentiation, and plasticity in vertebrate species
Nagahama, Y., Chakraborty, T., Paul-Prasanth, B., Ohta, K., & Nakamura, M. (2021) · Physiological Reviews · doi:10.1152/physrev.00044.2019 · Cited by 346
Metadata
- Authors
- Smith, C. A., & Sinclair, A. H.
- Venue
- BioEssays
- Publisher
- Wiley
- Published
- 2004-01-21
- Volume
- 26
- Issue
- 2
- Pages
- 120-132
- ISSN
- 0265-9247 (ISSN-L)
- 1521-1878
- OpenAlex
- W1967103103
- Cited by
- 353
- References
- 2
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- closed
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