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Cited by 177

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

Open access
Duboule, Denis·1992·BioEssays

Abstract

The potential of the vertebrate limb as a model system to study developmental mechanisms is particularly well illustrated by the analysis of the Hox gene network. These genes are probably involved in the establishment of patterns encoding positional information. Their functional organisation during both limb and trunk development are very similar and seem to involve the progressive activation in time, along the chromosome, of a battery of genes whose products could differentially instruct those cells where they are expressed. This process may be common to all organisms that develop according to an anterior‐posterior morphogenetic progression. The possible linkage of this system to a particular mechanism of segmentation as well as its phylogenetic implications are discussed.

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Metadata

Authors
Duboule, D.
Venue
BioEssays
Publisher
Wiley
Published
1992-06
Volume
14
Issue
6
Pages
375-384
ISSN
  • 0265-9247 (ISSN-L)
  • 1521-1878
OpenAlex
W1984844595
Cited by
177
References
2
FWCI
1.91
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution. https://app.cochat.ai/papers/10.1002/bies.950140606
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Duboule, D. (1992). The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution. BioEssays. https://doi.org/10.1002/bies.950140606

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.