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Ring‐current effects in the nmr of nucleic acids: A graphical approach
Abstract
The spatial dependence of the ring‐current magnetic anisotropy of nucleic acid bases is presented in a series of graphs in cylindrical coordinates. The curves may be used to calculate the ring‐current shift at a point in a cylinder of radius 10Å extending 8 Å above and below each ring of the base. These distance effects are found to influence considerably the predicted chemical shifts of nucleic acid protons, particularly in RNA duplexes. The contribution of polarization (electric field) effects and the diamagnetic anisotropy of individual atoms (local Δ χ) are briefly discussed.
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Cited by
Steyrleuthner, R., Schubert, M., Howard, I., Klaumünzer, B., Schilling, K., Chen, Z., Saalfrank, P., Laquai, F., Facchetti, A., & Neher, D. (2012) · Journal of the American Chemical Society · doi:10.1021/ja306844f · Cited by 458
Patel, D. J. (1979) · Accounts of Chemical Research · doi:10.1021/ar50136a002 · Cited by 147
PATEL, D. J. (1979) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1979.tb13265.x · Cited by 54
Modifications Modulate Anticodon Loop Dynamics and Codon Recognition of E. coli tRNAArg1,2
Cantara, W. A., Bilbille, Y., Kim, J., Kaiser, R., Leszczyńska, G., Malkiewicz, A., & Agris, P. F. (2012) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.12.054 · Cited by 36
Metadata
- Authors
- Giessner‐Prettre, C., Pullman, B., Borer, P. N., Kan, L., & Ts'O, P. O. P.
- Venue
- Biopolymers
- Publisher
- Wiley
- Published
- 1976-11
- Volume
- 15
- Issue
- 11
- Pages
- 2277-2286
- ISSN
- 0006-3525 (ISSN-L)
- 1097-0282
- OpenAlex
- W2021613285
- Cited by
- 180
- References
- 0
- FWCI
- 11.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Giessner‐Prettre, C., Pullman, B., Borer, P. N., Kan, L., & Ts'O, P. O. P. (1976). Ring‐current effects in the nmr of nucleic acids: A graphical approach. Biopolymers. https://doi.org/10.1002/bip.1976.360151114
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