The DOI matches its Crossref record.
Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus
Abstract
Fasting and postprandial intragastric bile acid concentrations have been estimated and compared in patients with complications of Barrett's oesophagus, patients with Barrett's oesophagus without complications, patients with oesophagitis and a group of normal subjects who acted as controls. There was no significant difference in fasting intragastric bile acid concentrations between the groups. Postprandial bile acid concentrations were significantly greater in the patients with complications of Barrett's than in the remaining groups at 60, 90 and 120 min. Significant concentrations of bile acids were seen in gastric juice of unaltered pH and may be undetected on intra-oesophageal pH monitoring. Duodenogastric reflux may be implicated in the pathogenesis of complications of Barrett's oesophagus.
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Cited by
Bile acids as carcinogens in human gastrointestinal cancers
Bernstein, H., Bernstein, C., Payne, C. M., Dvorakova, K., & Garewal, H. (2005) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2004.08.001 · Cited by 611
Duodenogastroesophageal reflux: Relationship to pH and importance in Barrett's esophagus
Champion, G., Richter, J. E., Vaezi, M. F., Singh, S., & Alexander, R. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90123-6 · Cited by 455
Jankowski, J. A., Harrison, R. F., Perry, I., Balkwill, F., & Tselepis, C. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03411-5 · Cited by 316
Metadata
- Authors
- Gillen, P., Keeling, P., Byrne, P. J., Healy, M., O'Moore, R. R., & Hennessy, T. P. J.
- Venue
- Journal of British Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 1988-06-01
- Volume
- 75
- Issue
- 6
- Pages
- 540-543
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W2031374397
- Cited by
- 187
- References
- 0
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus. https://app.cochat.ai/papers/10.1002/bjs.1800750612
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- Gillen, P., Keeling, P., Byrne, P. J., Healy, M., O'Moore, R. R., & Hennessy, T. P. J. (1988). Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus. Journal of British Surgery. https://doi.org/10.1002/bjs.1800750612
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
