The DOI matches its Crossref record.
Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone
Abstract
Three hundred and eighty-one women with operable breast cancer aged over 70 years were randomly allocated to 40 mg tamoxifen daily and optimal surgery or to tamoxifen alone. At a median follow-up of 34 months there was no demonstrable difference in survival rate or in quality of life between the two treatment groups. More patients treated with tamoxifen alone had a subsequent change of management and this was usually an operation for local treatment failure. This progression to surgery has not been shown to be disadvantageous and the study will continue. Informed consent for randomization was difficult to obtain, leading to the exclusion of eligible patients, and it is therefore proposed to include non-randomized patients in a total cohort study.
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Citations
Cited by
Undertreatment Strongly Decreases Prognosis of Breast Cancer in Elderly Women
Bouchardy, C., Rapiti, E., Fioretta, G., Laissue, P., Neyroud-Caspar, I., Schäfer, P., Kurtz, J., Sappino, A.-P., & Vlastos, G. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.02.046 · Cited by 512
Johnston, S. J., Kenny, F. S., Syed, B. M., Robertson, J. F. R., Pinder, S. E., Winterbottom, L., Ellis, I. O., Blamey, R. W., & Cheung, K. L. (2012) · Annals of Oncology · doi:10.1093/annonc/mdr630 · Cited by 55
Metadata
- Authors
- Bates, T., Riley, D. L., Houghton, J., Fallowfield, L., & Baum, M.
- Venue
- Journal of British Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 1991-05-01
- Volume
- 78
- Issue
- 5
- Pages
- 591-594
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W2092326774
- Cited by
- 191
- References
- 0
- FWCI
- 3.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. https://app.cochat.ai/papers/10.1002/bjs.1800780523
- The paper
- Bates, T., Riley, D. L., Houghton, J., Fallowfield, L., & Baum, M. (1991). Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. Journal of British Surgery. https://doi.org/10.1002/bjs.1800780523
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
