The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Risk factors for faecal incontinence after rectal cancer treatment
Abstract
Background: Low anterior resection (LAR) may result in faecal incontinence. This study aimed to identify risk factors for long-term faecal incontinence after total mesorectal excision (TME) with or without preoperative radiotherapy (PRT). Methods: Between 1996 and 1999, patients with operable rectal cancer were randomized to TME with or without PRT. Eligible patients who underwent LAR were studied retrospectively at 2 years (399 patients) and 5 years (339) after TME. Results: At 5 years after surgery faecal incontinence was reported by 61·5 per cent of patients who had PRT and 38·8 per cent of those who did not (P < 0·001). Excessive blood loss and height of the tumour were associated with long-term faecal incontinence, but only in patients treated with PRT. Conclusion: Faecal incontinence is likely to occur after PRT and TME, especially when the perineum is irradiated.
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Cites
Preoperative Radiotherapy Combined with Total Mesorectal Excision for Resectable Rectal Cancer
Kapiteijn, E., Marijnen, C. A. M., Nagtegaal, I. D., Putter, H., Steup, W. H., Wiggers, T., Rutten, H. J. T., Pahlman, L., Glimelius, B., van Krieken, J. H. J. M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010580 · Cited by 4,205
Self-citationMarijnen, C. A. M., van de Velde, C. J. H., Putter, H., van den Brink, M., Maas, C. P., Martijn, H., Rutten, H. J., Wiggers, T., Kranenbarg, E. K., Leer, J.-W. H., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.05.256 · Cited by 650
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Cited by
Japanese Society for Cancer of the Colon and Rectum, Watanabe, T., Muro, K., Ajioka, Y., Hashiguchi, Y., Ito, Y., Saito, Y., Hamaguchi, T., Ishida, H., Ishiguro, M., et al. (2018) · International Journal of Clinical Oncology · doi:10.1007/s10147-017-1101-6 · Cited by 2,467
Hashiguchi, Y., Muro, K., Saito, Y., Ito, Y., Ajioka, Y., Hamaguchi, T., Hasegawa, K., Hotta, K., Ishida, H., Ishiguro, M., et al. (2020) · International Journal of Clinical Oncology · doi:10.1007/s10147-019-01485-z · Cited by 1,922
Bryant, C. L., Lunniss, P. J., Knowles, C. H., Thaha, M. A., & Chan, C. L. (2012) · The Lancet Oncology · doi:10.1016/s1470-2045(12)70236-x · Cited by 640
Bregendahl, S., Emmertsen, K. J., Lous, J., & Laurberg, S. (2013) · Colorectal Disease · doi:10.1111/codi.12244 · Cited by 332
Metadata
- Authors
- cooperative clinical investigators of the Dutch Total Mesorectal Excision trial, Lange, M. M., den Dulk, M., Bossema, E. R., Maas, C. P., Peeters, K. C. M. J., Rutten, H. J., Klein Kranenbarg, E., Marijnen, C. A. M., & van de Velde, C. J. H.
- Venue
- British Journal of Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-06-19
- Volume
- 94
- Issue
- 10
- Pages
- 1278-1284
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W1971838125
- Cited by
- 190
- References
- 2
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
