Natural Monoterpenes: Much More Than Only a Scent
Abstract
Terpenes are a widespread group of secondary metabolites that can be found in various family plants such as the Lamiaceae. In view of their numerous valuable biological activities, the industrial production of concrete terpenes and essential oils rich in the substances is intensively studied. Monoterpenes constitute a significant part of the whole group of the aforementioned secondary metabolites. This is due to their numerous biological activities and their ability to permeate the skin. Despite the fact that these substances have gain popularity, they are not comprehensively characterized. The presented review is based on studies of the biological activities of the most important monoterpenes and the essential oils rich in these compounds. The authors focused attention on antioxidant activity, inhibition towards acetyl- and butyrylcholinesterase, and α-amylase and α-glucosidase, antifungal, hepatoprotective, sedative properties, and their skin permeation enhancement.
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Linalool improves the antioxidant potential of many essential oils by acting in synergy with other components.
“Despite its lower antioxidant activity compared to other monoterpenes due to the lack of conjugated double bonds, linalool has been shown to improve the antioxidant potential of many essential oils by acting in synergy with other components (Wojtunik-Kulesza et al., 2019).”
From Exploring the Therapeutic Potential of Phytochemicals in Alzheimer’s Disease: Focus on Polyphenols and Monoterpenes (2022) · cites this paper as Wojtunik-Kulesza et al., 2019
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References 133 · Cited by 137
- Authors
- Wojtunik‐Kulesza, K. A., Kasprzak, K., Oniszczuk, T., & Oniszczuk, A.
- Affiliations
- Medical University of Lublin (PL)
- Department of Inorganic Chemistry, Faculty of Pharmacy Medical University of Lublin 4 A. Chodźki Street 20-093 Lublin Poland
- University of Life Sciences in Lublin (PL)
- Corresponding author
- Wojtunik‐Kulesza, Karolina A.
- Venue
- Chemistry & Biodiversity
- Publisher
- Wiley
- Published
- 2019-11-08
- Volume
- 16
- Issue
- 12
- Pages
- e1900434-e1900434
- ISSN
- 1612-1872 (ISSN-L)
- 1612-1880
- OpenAlex
- W2977736925
- Cited by
- 137
- References
- 133
- Citations by year
- 2026: 22 · 2025: 22 · 2024: 13 · 2023: 26 · 2022: 23 · 2021: 19 · 2020: 11 · 2019: 1
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemistry & Biodiversity (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- monoterpenes, essential oils, secondary metabolites, Lamiaceae, antioxidant activity, acetylcholinesterase inhibition, butyrylcholinesterase inhibition, α-amylase inhibition, α-glucosidase inhibition, antifungal activity, hepatoprotection, sedative effects, skin permeation enhancement
- MeSH terms
- Alzheimer Disease, Animals, Antioxidants, Cholinesterases, Oils, Volatile, Oxidative Stress, Lamiaceae, Monoterpenes, NF-E2-Related Factor 2
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