Isocitrate dehydrogenase activity and its regulation by estradiol in tissues of rats of various ages

The activity and hormonal regulation of NAD‐ and NADP‐linked isocitrate dehydrogenase (EC.1.1.1.41 and EC.1.1.1.42, respectively) in the brain, liver and kidney cortex of female rats of various ages was investigated. The activity of NAD‐ICDH of brain was greater than extramitochondrial (‐c) or in…