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Intramolecular Dimers: A New Design Strategy for Fluorescence‐Quenched Probes
Open accessAbstract
Fluorogenic probes dual‐labeled with reporter and quencher dyes use a change in fluorescence to monitor biochemical events (e.g., substrate binding or enzyme digestion). Such events change the reporter–quencher distance, which affects fluorescence. Recently, it is has been shown that static quenching through intramolecular dimers is an important mechanism that can sometimes be more efficient than Förster resonance energy transfer (FRET).
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Blackman, M. J., Corrie, J. E. T., Croney, J. C., Kelly, G., Eccleston, J. F., & Jameson, D. M. (2002) · Biochemistry · doi:10.1021/bi0263661 · Cited by 73
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Zhou, K., Liu, H., Zhang, S., Huang, X., Wang, Y., Huang, G., Sumer, B. D., & Gao, J. (2012) · Journal of the American Chemical Society · doi:10.1021/ja300176w · Cited by 344
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Metadata
- Authors
- Johansson, M. K., & Cook, R. M.
- Venue
- Chemistry – A European Journal
- Publisher
- Wiley
- Published
- 2003-07-11
- Volume
- 9
- Issue
- 15
- Pages
- 3466-3471
- ISSN
- 0947-6539 (ISSN-L)
- 1521-3765
- OpenAlex
- W2076051033
- Cited by
- 185
- References
- 1
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Johansson, M. K., & Cook, R. M. (2003). Intramolecular Dimers: A New Design Strategy for Fluorescence‐Quenched Probes. Chemistry – A European Journal. https://doi.org/10.1002/chem.200304941
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.