The DOI matches its Crossref record.
Comparison of fluorine‐18 fluorodeoxyglucose positron emission tomography and Ga‐67 scintigraphy in evaluation of lymphoma
Open accessAbstract
BACKGROUND: The accuracy of fluorodeoxyglucose positron emission tomography (FDG‐PET; dual‐head camera with attenuation correction) and Ga‐67 scintigraphy was compared to identify disease sites in patients with Hodgkin disease (HD) and intermediate and high‐grade non‐Hodgkin lymphoma (NHL) at initial diagnosis or clinical recurrence. METHODS: Fifty‐one contemporaneous FDG‐PET and Ga‐67 scintigraphies were performed on patients with NHL (35 intermediate grade, 3 high grade) or HD (13 patients). Sites of disease were correlated on a site‐by‐site basis on FDG‐PET and Ga‐67 images. Tumor‐to‐background (T/B) ratios were obtained for both techniques. Discordant FDG‐PET and Ga‐67 findings were correlated with computed tomography findings or clinical evaluation including repeat FDG‐PET scans obtained after therapy. RESULTS: Fluorodeoxyglucose positron emission tomography was positive at all 158 sites in 51 patients compared with 113 sites in 41 positive studies with Ga‐67 scintigraphy (single positron emission computed tomography [SPECT] and/or planar images). In 44 patients who had complete Ga‐67 SPECT data on all tumor sites, FDG‐PET was positive at 126 sites and Ga‐67 SPECT was positive at 81 sites. Ga‐67 SPECT failed to demonstrate disease at 45 sites (35.7%). In 10 of 44 patients, Ga‐67 SPECT completely failed to detect any disease at 22 of 45 sites (17.5%) and partially identified disease sites at 23 of 45 sites (18.2%) in 11 patients regardless of the tumor site and histology. In these patients, the lesions measured between 0.6 and 14.0 cm by CT. Fluorodeoxyglucose positron emission tomography revealed higher stage disease in 13 patients compared with Ga‐67 imaging. Tumor‐to‐background ratios were statistically different between the two techniques with higher ratios obtained with FDG‐PET (P < 0.0001). CONCLUSIONS: In imaging aggressive lymphoma and HD before therapy, FDG‐PET has significantly higher site and patient sensitivity than Ga‐67 scintigraphy (100% vs. 71.5% and 100% vs. 80.3%, respectively). The change in disease stage by FDG‐PET may result in a change in therapy strategy. Cancer 2002;94:879–88. © 2002 American Cancer Society. DOI 10.1002/cncr.10336
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Blodgett, T. M., Meltzer, C. C., & Townsend, D. W. (2007) · Radiology · doi:10.1148/radiol.2422051113 · Cited by 387
Metadata
- Authors
- Kostakoglu, L., Leonard, J. P., Kuji, I., Coleman, M., Vallabhajosula, S., & Goldsmith, S. J.
- Venue
- Cancer
- Publisher
- Wiley
- Published
- 2002-02-15
- Volume
- 94
- Issue
- 4
- Pages
- 879-888
- ISSN
- 0008-543X (ISSN-L)
- 1097-0142
- OpenAlex
- W2004683676
- Cited by
- 212
- References
- 0
- FWCI
- 11.52
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Comparison of fluorine‐18 fluorodeoxyglucose positron emission tomography and Ga‐67 scintigraphy in evaluation of lymphoma. https://app.cochat.ai/papers/10.1002/cncr.10336
- The paper
- Kostakoglu, L., Leonard, J. P., Kuji, I., Coleman, M., Vallabhajosula, S., & Goldsmith, S. J. (2002). Comparison of fluorine‐18 fluorodeoxyglucose positron emission tomography and Ga‐67 scintigraphy in evaluation of lymphoma. Cancer. https://doi.org/10.1002/cncr.10336
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
