The DOI matches its Crossref record.
Primary malignant neoplasms of the appendix: A population‐based study from the surveillance, epidemiology and end‐results program, 1973–1998
Open accessAbstract
BACKGROUND: Cancer of the appendix is an uncommon disease that is rarely suspected rarely before surgery. Although several case series of these tumors have been published, little research has been anchored in population‐based data on cancer of the appendix. METHODS: This analysis included all actively followed cases of appendiceal neoplasms reported to the National Cancer Institute's Surveillance, Epidemiology and End‐Results (SEER) program between 1973 and 1998. Tumors were classified as “colonic type” adenocarcinoma, mucinous adenocarcinoma, signet ring cell carcinoma, goblet cell carcinoid, and “malignant carcinoid” (SEER only collects data on carcinoids specifically classified as malignant). We compared incidence, overall survival and survival rates by extent of disease at diagnosis. RESULTS: Between 1973 and 1998, 2117 appendiceal malignancies were reported to the SEER program, of which 1645 cases were included in the analysis. Age‐adjusted incidence of cancer of the appendix was 0.12 cases per 1,000,000 people per year. Demographic characteristics of patients with goblet cell carcinoid tumors were midway between those of patients with malignant carcinoid and all types of adenocarcinomas. After controlling for age and extent of disease at diagnosis, the overall survival rate for patients diagnosed between 1983 and 1997 (n = 1061) was significantly worse for those with signet ring cell carcinoma than for those with any other tumor type (P < 0.01). In addition, overall survival rates were better for patients with malignant carcinoid (P = 0.01). CONCLUSIONS: Demographic characteristics of patients with cancer of the appendix vary by histology. Except for signet ring cell carcinoma and malignant carcinoid, the extent of disease at time of diagnosis is a more important predictor of survival than histology. Cancer 2002;94:3307–12. © 2002 American Cancer Society. DOI 10.1002/cncr.10589
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Colorectal cancer statistics, 2020
Siegel, R. L., Miller, K. D., Goding Sauer, A., Fedewa, S. A., Butterly, L. F., Anderson, J. C., Cercek, A., Smith, R. A., & Jemal, A. (2020) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21601 · Cited by 4,880
Appendiceal Mucinous Neoplasms: A Clinicopathologic Analysis of 107 Cases
Misdraji, J., Yantiss, R. K., Graeme-Cook, F. M., Balis, U. J., & Young, R. H. (2003) · The American Journal of Surgical Pathology · doi:10.1097/00000478-200308000-00006 · Cited by 555
Appendiceal neoplasms and pseudomyxoma peritonei: A population based study
Smeenk, R. M., van Velthuysen, M. L. F., Verwaal, V. J., & Zoetmulder, F. A. N. (2008) · European Journal of Surgical Oncology (EJSO) · doi:10.1016/j.ejso.2007.04.002 · Cited by 555
Pape, U.-F., Perren, A., Niederle, B., Gross, D., Gress, T., Costa, F., Arnold, R., Denecke, T., Plöckinger, U., Salazar, R., et al. (2012) · Neuroendocrinology · doi:10.1159/000335629 · Cited by 465
Appendiceal Mucinous Neoplasms: Diagnosis and Management
Shaib, W. L., Assi, R., Shamseddine, A., Alese, O. B., Staley, C., Memis, B., Adsay, V., Bekaii-Saab, T., & El-Rayes, B. F. (2017) · The Oncologist · doi:10.1634/theoncologist.2017-0081 · Cited by 265
Metadata
- Authors
- McCusker, M. E., Coté, T. R., Clegg, L. X., & Sobin, L. H.
- Venue
- Cancer
- Publisher
- Wiley
- Published
- 2002-06-12
- Volume
- 94
- Issue
- 12
- Pages
- 3307-3312
- ISSN
- 0008-543X (ISSN-L)
- 1097-0142
- OpenAlex
- W2022597059
- Cited by
- 610
- References
- 0
- FWCI
- 8.47
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Primary malignant neoplasms of the appendix: A population‐based study from the surveillance, epidemiology and end‐results program, 1973–1998. https://app.cochat.ai/papers/10.1002/cncr.10589
- The paper
- McCusker, M. E., Coté, T. R., Clegg, L. X., & Sobin, L. H. (2002). Primary malignant neoplasms of the appendix: A population‐based study from the surveillance, epidemiology and end‐results program, 1973–1998. Cancer. https://doi.org/10.1002/cncr.10589
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
