Rebiopsy of non–small cell lung cancer patients with acquired resistance to epidermal growth factor receptor‐tyrosine kinase inhibitor: Comparison between T790M mutation‐positive and mutation‐negative populations
Hata, Akito, Katakami, Nobuyuki, Yoshioka, Hiroshige, Takeshita, Jumpei, Tanaka, Kosuke, Nanjo, Shigeki, Fujita, Shiro, Kaji, Reiko, Imai, Yukihiro, Monden, Kazuya, Matsumoto, Takeshi, Nagata, Kazuma, Otsuka, Kyoko, Tachikawa, Ryo, Tomii, Keisuke, Kunimasa, Kei, Iwasaku, Masahiro, Nishiyama, Akihiro, Ishida, Tadashi, Nishimura, Yoshihiro·2013·Cancer
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Items 101–179 of 179
- A Neuro-oncologist’s Perspective on Management of Brain Metastases in Patients with EGFR Mutant Non-small Cell Lung CancerTresa Michelle McGranahan, Seema Nagpal · 2017 · Current Treatment Options in Oncology
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- Distinct Progression and Efficacy of First-Line Osimertinib Treatment According to Mutation Subtypes in Metastatic NSCLC Harboring EGFR MutationsYuki Takeyasu, Tatsuya Yoshida, Ken Masuda, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Yasushi Goto, Hidehito Horinouchi, Noboru Yamamoto, Yuichiro Ohe · 2024 · JTO Clinical and Research Reports
- Comparison of T790M Acquisition After Treatment With First- and Second-Generation Tyrosine-Kinase Inhibitors: A Systematic Review and Network Meta-AnalysisPo‐Chun Hsieh, Yao‐Kuang Wu, Chun-Yao Huang, Mei-Chen Yang, Chan‐Yen Kuo, I‐Shiang Tzeng, Chou‐Chin Lan · 2022 · Frontiers in Oncology
- Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSFStephanie Kim Cheok, Azeet Narayan, Anna Arnal Estape, Scott N. Gettinger, Sarah B. Goldberg, Harriet M. Kluger, Don X. Nguyen, Abhijit A. Patel, Veronica Chiang · 2021 · JCO Precision Oncology
- A sensitive and practical method to detect the T790M mutation in the epidermal growth factor receptorJing Zhao, HUA-HUA FENG, Jinyin Zhao, LI-CHENG LIU, Feifei Xie, Yan Xu, MIN-JIANG CHEN, Wei Zhong, Longyun LI, HAN-PING WANG et al. · 2016 · Oncology Letters
- Post-Progression Survival in Secondary EGFR T790M-Mutated Non-Small-Cell Lung Cancer Patients With and Without Osimertinib After Failure of a Previous EGFR TKIChi‐Lu Chiang, Hsu-Ching Huang, Chia‐I Shen, Yung‐Hung Luo, Yuh‐Min Chen, Chao‐Hua Chiu · 2020 · Targeted Oncology
- T790M mutant copy number quantified via ddPCR predicts outcome after osimertinib treatment in lung cancerJacky Yu-Chung Li, Jcm Ho, Kam-Hung Wong · 2018 · Oncotarget
- Detection of epidermal growth factor receptor gene T790M mutation in cytology samples using the cobas ® EGFR mutation testMiyako Satouchi, Hiroshi Tanaka, Hiroshige Yoshioka, Tadasuke Shimokawaji, Keiko Mizuno, Koji Takeda, Ichiro Yoshino, Takashi Seto, Takayasu Kurata, Naoki Tashiro et al. · 2017 · Lung Cancer
- Clinical Efficacy of Afatinib Treatment for a Patient with Leptomeningeal CarcinomatosisYo Kawaguchi, Jun Hanaoka, Hideki Hayashi, Naoki Mizusaki, Hirotoshi Iihara, Yoshinori Itoh, Tadashi Sugiyama · 2016 · Chemotherapy
- Continuation of gefitinib beyond progression in patients with EGFR mutation-positive non-small-cell lung cancer: A phase II single-arm trialSung Won Lim, Sehhoon Park, Youjin Kim, Jang Ho Cho, Song Ee Park, Hansang Lee, Hee Kyung Kim, Sung Min Kim, Jong Mu Sun, Se‐Hoon Lee et al. · 2018 · Lung Cancer
- A Randomized, Open-Label, Phase II Study Comparing Pemetrexed Plus Cisplatin Followed by Maintenance Pemetrexed versus Pemetrexed Alone in Patients with Epidermal Growth Factor Receptor (EGFR)-Mutant Non-small Cell Lung Cancer after Failure of First-Line EGFR Tyrosine Kinase Inhibitor: KCSG-LU12-13Kwai Han Yoo, Su Jin Lee, Jinhyun Cho, Ki Hyeong Lee, Keon Uk Park, Ki Hwan Kim, Eun Kyung Cho, Yoon Hee Choi, Hye Ryun Kim, Hoon‐Gu Kim et al. · 2018 · Cancer Research and Treatment
- Response to pemetrexed rechallenge after acquired resistance of EGFR-TKI in a patient with advanced NSCLCShuai Li, Fangyu Zhou, Shengxiang Ren, Caicun Zhou · 2014 · Lung Cancer
- Precision cytopathology: expanding opportunities for biomarker testing in cytopathologyAdriana Morales Sánchez, Therese J. Bocklage · 2018 · Journal of the American Society of Cytopathology
- Overexpression of Reactive Oxygen Species Modulator 1 Predicts Unfavorable Clinical Outcome in EGFR-Mutant Lung Adenocarcinomas Treated With Targeted TherapyWon Gun Kwack, Ji‐Youn Sung, Seung Hyeun Lee · 2021 · Frontiers in Oncology
- Discovery of the allosteric inhibitor from actinomyces metabolites to target EGFRCSTMLR mutant protein: molecular modeling and free energy approachRavi Prakash Saini, Sonali Kumari, Aditi Bhatnagar, Amit Kant Singh, Abha Mishra · 2023 · Scientific Reports
- Expert consensus on the use of third-generation EGFR-TKIs in EGFR-mutated advanced non-small cell lung cancer with various T790M mutations post-resistance to first-/second-generation EGFR-TKIsJietao Ma, Le‐Tian Huang, Cheng‐Bo Han · 2024 · Therapeutic Advances in Medical Oncology
- Rationale and Study Design of the IRENE-Trial (NVALT-16): A Phase II Trial to Evaluate Iressa Rechallenge in Advanced NSCLC Patients With an Activating EGFR Mutation Who Responded to an EGFR-TKI Used As First-Line or Previous TreatmentJustine Leonie Kuiper, Daniëlle A.M. Heideman, Tom Würdinger, Katrien Grünberg, Harry J.M. Groen, Egbert Frederik Smit · 2014 · Clinical Lung Cancer
- Effect of AXL on the epithelial-to-mesenchymal transition in non-small cell lung cancerXueming Ying, Jun Chen, Xueming Huang, Peng Huang, Shao-Cong Yan · 2017 · Experimental and Therapeutic Medicine
- Higher osimertinib introduction rate achieved by multiple repeated rebiopsy after acquired resistance to first/second generation EGFR‐TKIsTaira Ninomaru, Akito Hata, Chiyuki Kokan, Hideaki Okada, Hirotaka Tomimatsu, Jun Ishida · 2021 · Thoracic Cancer
- Frequency of T790M mutations after progression on epidermal growth factor receptor tyrosine kinase inhibitor in metastatic non-small cell lung cancer in Indian patients: real-time data from tertiary cancer hospitalVenkata Pradeep Babu Koyyala, Ullas Batra, Parveen Jain, Mansi Sharma, Pankaj Goyal, Pavani Medisetty, Ankush Jajodia, Udip Maheshwari · 2018 · Lung India
- Partial response to carboplatin in an RRx-001 pretreated patient with EGFR-inhibitor-resistance and T790M-negative NSCLCCorey Allan Carter, Bryan T. Oronsky, Scott Z. Caroen, Jan J. Scicinski, Pedro Cabrales, Aiste Degesys, Christina E. Brzezniak · 2016 · Respiratory Medicine Case Reports
- A case of resistance to tyrosine kinase inhibitor therapyYanjun Xu, Zhiyu Huang, Lei Gong, Yun Fan · 2017 · Anti-Cancer Drugs
- Successful Treatment with Osimertinib and Chemotherapy in a Non–Small Cell Lung Cancer Patient with EGFR Mutation and Meningeal CarcinomatosisHironori Yoshida, Masahiro Ooi, Young Hak Kim · 2018 · Journal of Thoracic Oncology
- Brain metastases in EGFR-positive non-small cell lung cancer: the way to the sanctuary becomes less windingAntonio Passaro, Letizia Gianoncelli, Valeria Stati, Filippo de Marinis · 2019 · Annals of Translational Medicine
- Dramatic intracranial response to osimertinib in a poor performance status patient with lung adenocarcinoma harboring the epidermal growth factor receptor T790M mutation: A case reportTakehiro Uemura, Tetsuya Oguri, Minami Okayama, Hiromi Furuta, Yoshihiro Kanemitsu, Osamu Takakuwa, Hirotsugu Ohkubo, Masaya Takemura, Ken Maeno, Yutaka Ito et al. · 2017 · Molecular and Clinical Oncology
- Chromosome 7 Multiplication in EGFR-positive Lung Carcinomas Based on Tissue Microarray AnalysisEvangelos Tsiambas, NICHOLAS S. MASTRONIKOLIS, Alicia Yioli Lefas, Stavros N Georgiannos, Vasileios Ragos, Panagiotis P Fotiades, Nikolaos Tsoukalas, Nikolaos Kavantzas, Andreas Karameris, Dimitrios Peschos et al. · 2017 · In Vivo
- T790M Correlates with Longer Progression-free Survival in Non-small Cell Lung Carcinomas HarboringEGFRMutationsYoshihito Kogure, Fumie Shigematsu, Masahide Oki, Hideo Saka · 2018 · In Vivo
- CT Radiomics Predict EGFR-T790M Resistance Mutation in Advanced Non-Small Cell Lung Cancer Patients After Progression on First-line EGFR-TKIXin Tang, Yuan Li, Li-Ting Shen, Wei‐Feng Yan, Wen-Lei Qian, Zhi‐gang Yang · 2023 · Academic Radiology
- Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidenceYosuke Togashi, Hidetoshi Hayashi, Kazuhiko Nakagawa, Kazuto Nishio · 2014 · Drug Design Development and Therapy
- Efficacy of Osimertinib in EGFR-Mutated Advanced Non-small-Cell Lung Cancer With Different T790M Status Following Resistance to Prior EGFR-TKIs: A Systematic Review and Meta-analysisXiao-Fang Yi, Jun Song, Ruo-Lin Gao, Li Sun, Zhixuan Wu, Shuling Zhang, Le‐Tian Huang, Jie‐Tao Ma, Cheng‐Bo Han · 2022 · Frontiers in Oncology
- Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with GefitinibRiziero Esposito Abate, Raffaella Pasquale, Alessandra Sacco, Maria Carmela Piccirillo, Alessandro Morabito, Paolo Bidoli, Giovanna Finocchiaro, Rita Chiari, Luisa Foltran, Roberta Buosi et al. · 2019 · Cancers
- Readministration of EGFR Tyrosine Kinase Inhibitor in Non-small Cell Lung Cancer Patients after Initial Failure, What Affects its Efficacy?Ze-Rui Zhao, Wěi Li, Hao Long · 2014 · Scientific Reports
- Unravelling signal escape through maintained EGFR activation in advanced non-small cell lung cancer (NSCLC): new treatment optionsJordi Remón, Benjamin Besse · 2016 · ESMO Open
- Predictors of Acquired T790M Mutation in Patients Failing First- or Second-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase InhibitorsChee-Shee Chai, Chong Kin Liam, Mau Ern Poh, Diana Bee‐Lan Ong, Yong‐Kek Pang, Phaik‐Leng Cheah, Gwo Fuang Ho, Adlinda Alip · 2020 · Cancer Management and Research
- Methodological comparison of the allele refractory mutation system and direct sequencing for detecting EGFR mutations in NSCLC, and the association of EGFR mutations with patient characteristicsMinmin Wu, Xiaodong Pan, Yaya Xu, Siying Wu, Xiuling Wu, Bicheng Chen · 2018 · Oncology Letters
- Thick-wall cavity predicts worse progression-free survival in lung adenocarcinoma treated with first-line EGFR-TKIsFei Zhou, Wanrong Ma, Wěi Li, Huijuan Ni, Guanghui Gao, Xiaoxia Chen, Jie Zhang, Jingyun Shi · 2018 · BMC Cancer
- Investigation of molecular mechanism leading to gefitinib and osimertinib resistance against EGFR tyrosine kinase: molecular dynamics and binding free energy calculationAmit Kant Singh, Abha Mishra · 2022 · Journal of Biomolecular Structure and Dynamics
- Negative impact of malignant effusion on osimertinib treatment for non-small cell lung cancer harboring EGFR mutationTakahisa Kawamura, Hirotsugu Kenmotsu, Haruki Kobayashi, Shota Omori, Kazuhisa Nakashima, Kazushige Wakuda, Akira Ono, Tateaki Naito, Haruyasu Murakami, Keita P. Mori et al. · 2019 · Investigational New Drugs
- Current chemotherapeutic regimens for brain metastases treatmentJoo Yeon Nam, Barbara Jane O'Brien · 2017 · Clinical & Experimental Metastasis
- Epidermal Growth Factor Receptor Mutation Detection in Cerebrospinal Fluid of Lung Adenocarcinoma Patients with Leptomeningeal MetastasisRuofan Huang, Mengxi Ge, Xinli Zhou, Xiaoyu Ji, Li Liao, Xiaohua Liang, Qiong Zhan · 2018 · Cancer Biotherapy and Radiopharmaceuticals
- Differential MicroRNA Expression between EGFR T790M and L858R Mutated Lung CancerJi Yeon Kim, Woo Jeong Lee, Ha Young Park, Ahrong Kim, Dong‐Hoon Shin, Chang Hun Lee · 2018 · Journal of Pathology and Translational Medicine
- High Tumor Mutation Burden Is Associated with Poor Clinical Outcome in EGFR-Mutated Lung Adenocarcinomas Treated with Targeted TherapyJi‐Youn Sung, Dong-Won Park, Seung Hyeun Lee · 2022 · Biomedicines
- Successful treatment with weekly high-dose erlotinib against meningeal metastases from epidermal growth factor receptor (EGFR)-mutated lung adenocarcinomaRyota Kanemaru, Yoshiteru Morio, Hidenori Takekawa, Hitomi Jo, Fumiko Kasuga, Ryo Koyama, Satomi Shiota, Tetsutaro Nagaoka, Kazuhisa Takahashi · 2016 · Respiratory Investigation
- Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNAMasaki Hanibuchi, Akira Kanoh, Takuya Kuramoto, Tatsuro Saito, Makoto Tobiume, Atsuro Saijo, Hiroyuki Kozai, Mayo Kondo, Shun Morizumi, Hiroto Yoneda et al. · 2019 · Oncotarget
- Novel allosteric inhibitor to target drug resistance in EGFR mutant: molecular modelling and free energy approachAmit Singh, Ravi Prakash Saini, Abha Mishra · 2022 · Molecular Simulation
- Technical Validation and Clinical Implications of Ultrasensitive PCR Approaches for EGFR-Thr790Met Mutation Detection in Pretreatment FFPE Samples and in Liquid Biopsies from Non-Small Cell Lung Cancer PatientsJavier Simarro, Gema Pérez-Simó, Nuria Mancheño, Emilio Ansótegui, Carlos Francisco Muñoz-Núñez, José Gómez‐Codina, Óscar Juan, Sarai Palanca · 2022 · International Journal of Molecular Sciences
- Challenges in the Management of EGFR-Mutated Non-Small Cell Lung Cancer Patients with Acquired Resistance to Tyrosine Kinase InhibitorsJustine Leonie Kuiper, Egbert Frederik Smit · 2014 · Oncology
- Actualización de las recomendaciones para la determinación de biomarcadores en el carcinoma de pulmón avanzado de célula no pequeña. Consenso Nacional de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Oncología MédicaFernando López‐Ríos, Javier de Castro, Ángel Concha, Pilar Garrido, Javier Gómez‐Román, Dolores Isla, José Ramírez, Luis G Paz-Ares, Julián Sanz‐Ortega, Enriqueta Felip · 2014 · Revista Española de Patología
- The Feasibility of Interventional Pulmonology Methods for Detecting the T790M Mutation after the First or Second-Generation EGFR-TKI Resistance of Non-Small Cell Lung CancerWen‐Chien Cheng, Yi‐Cheng Shen, Chieh‐Lung Chen, Wei-Chih Liao, Hung-Jen Chen, Te‐Chun Hsia, Chia‐Hung Chen, Chih‐Yen Tu · 2022 · Diagnostics
- Prevalence of T790M mutation among TKI-therapy resistant Lebanese lung cancer patients based on liquid biopsy analysis: a first report from a major tertiary care centerHazem I. Assi, Arafat Tfayli, Nada Assaf, Sarah Abou Daya, Aram Bidikian, Dima Kawsarani, Puzant Fermanian, Ghazi S Zaatari, Rami A. Mahfouz · 2019 · Molecular Biology Reports
- Harnessing cuproptosis: a new avenue for targeted cancer therapiesAnil Dharavath, Sivkan Kaur, PV Drupad Mohan, Santosh Kumar Guru · 2025 · APOPTOSIS
- Acquired Resistance to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancers: The Role of Next-Generation Sequencing on Endobronchial Ultrasound–Guided Transbronchial Needle Aspiration SamplesElena Guerini‐Rocco, Antonio Passaro, Chiara Casadio, Valeria Midolo De Luca, Juliana Guarize, Filippo de Marinis, Davide Vacirca, Massimo C.P. Barberis · 2018 · Archives of Pathology & Laboratory Medicine
- Multi-line treatment with tyrosine kinase inhibitors enabled in 4-year survival for patient with stage IV lung adenocarcinoma: a case reportYan Yin, Jianwen Qin · 2020 · Annals of Palliative Medicine
- Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer and Eye Metastasis: Disease Relapse or a New Entity?Paul Zarogoulidis, Sofia Lampaki, Panos Chinelis, George Lazaridis, Sofia Baka, Aggeliki Rapti · 2016 · Medical Hypothesis Discovery & Innovation in Ophthalmology
- Promising Effects of Afatinib on Leptomeningeal Carcinomatosis Derived from Erlotinib-resistant Lung AdenocarcinomaAkimasa Sekine, Terufumi Kato, Tae Iwasawa, Tomohisa Baba, Akihiro Suido, Haruyasu Sakuranaka, Masaaki Futaki, Takashi Ogura · 2016 · Internal Medicine
- Effective Treatment With Afatinib of Lung Adenocarcinoma With Leptomeningeal Metastasis Harboring the Exon 18 p.G719A Mutation in the EGFR Gene Was Detected in Cerebrospinal Fluid: A Case ReportMa, Chunhua, Wang, Shuyuan, Mu, Ning, Li, Jinduo, Liu, Mei, Li, Lin, Jiang, Rong · 2020 · Frontiers in Oncology
- The optional approach of oncogene-addicted non-small cell lung cancer with brain metastases in the new generation targeted therapies eraAlessia Spagnuolo, Matteo Muto, Fabio Monaco, Giuseppe Colantuoni, Cesare Gridelli · 2019 · Translational Lung Cancer Research
- Epidermal growth factor receptor-Mutated Non-small-cell Lung Cancer with Intracranial Progressions and Stable Extracranial Diseases Benefit from Osimertinib Regardless of T790M Mutational StatusJun Liao, Yihua Huang, Jiadi Gan, Lanlan Pang, Wael Abdullah Sultan Ali, Yunpeng Yang, Likun Chen, Li Zhang, Wenfeng Fang · 2022 · Cancer Control
- Treatments and outcomes of advanced/recurrent non-small cell lung cancer harboring theEGFRT790M mutation: a retrospective observational study of 141 patients in JapanYuki Yamane, Ayako Shiono, Yoshiki Ishii, Kazutoshi Isobe, Eisaku Miyauchi, Kazuma Kishi, Makoto Nishino, Shunichi Sugawara, Ryo Ko, Nobuyuki Koyama et al. · 2016 · Japanese Journal of Clinical Oncology
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- T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma.Hanifeh Mirtavoos‐Mahyari, Azizollah Abbasi Dezfouli, Zahra Esfahani‐Monfared, Adnan Khosravi, Sharareh Seifi, Kambiz Sheikhy · 2022 · PubMed Central
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- Considerations on the Management of EGF Receptor-TKIs For Brain Metastases In EGFR -Mutant Lung Carcinoma PatientsMasato Shingyoji, Toshihiko Iuchi · 2015 · Lung Cancer Management
- The Clinical Strategy to Overcome EGFR-TKI Acquired Resistance for NSCLC PatientsLi Li · 2016 · International Journal of Cancer and Oncology
- Les rebiopsies : pourquoi ? Comment ?A. Saint-Paul, Julia Ballouhey, Alain Vergnenégre · 2017 · Revue des Maladies Respiratoires Actualités
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- Mutation abundance affects the efficacy of EGFR tyrosine kinase inhibitor readministration in non-small-cell lung cancer with acquired resistanceLinFang Wang, SuLong Jiang · 2014
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- EGFR plus MET Targeted Therapies for Overcoming Treatment Resistance in EGFR-Mutant Non-Small Cell Lung Cancer: A Case ReportMaria F. Martínez-Hernandez, Luis Lara‐Mejía, Carlos Izquierdo-Tolosa, Luis Antonio Cabrera-Miranda, Oscar G. Arrieta · 2024 · Oncology Research and Treatment
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- Clinical Outcomes of Different Generation EGFR TKIs in Susceptible EGFR ‐Mutated Advanced Nonsmall‐Cell Lung CancerChia‐Yu Kuo, Tien‐Chi Huang, Chih‐Jen Yang, Mei–Hsuan Lee, Jui‐Ying Lee, Ying‐Ming Tsai, Kuan‐Li Wu, Cheng‐Hao Chuang, Inn‐Wen Chong, Jen‐Yu Hung · 2025 · The Kaohsiung Journal of Medical Sciences
- Additional file 1 of Outcomes of surgery and subsequent therapy for central nervous system oligoprogression in EGFR-mutated NSCLC patientsPerng, Pang-Shuo, Hsu, Heng-Juei, Lee, Jung-Shun, Wang, Liang-Chao, Huang, Chih-Yuan, Tien, Chih-Hao, Lai, Yu-Hsuan, Su, Po-Lan, Hsu, Hao-Hsiang, Chen, Liang-Yi et al. · 2024 · Figshare
- Conséquences de la dérégulation de MET sur le phénotype des cancers bronchiques non à petites cellules EGFR mutés devenus résistant aux inhibiteurs de tyrosine kinase d’EGFRSimon Baldacci · 2017