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MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

Open access
Elad, Sharon, Cheng, Karis Kin Fong, Lalla, Rajesh V., Yarom, Noam, Hong, Catherine, Logan, Richard M., Bowen, Joanne, Gibson, Rachel, Saunders, Deborah P., Zadik, Yehuda, Ariyawardana, Anura, Correa, Maria Elvira, Ranna, Vinisha, Bossi, Paolo, for the Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO)·2020·Cancer

Abstract

Background: Mucositis is a significant toxicity of cancer therapy with numerous systemic sequelae. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for the management of mucositis. Methods: The literature was reviewed systematically to identify interventions for mucositis. Studies were rated according to the presence of major and minor flaws according to previously published criteria. The body of evidence for each intervention and in each treatment setting was assigned a level of evidence based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible. Results: The guideline covers evidence from 1197 publications related to oral or gastrointestinal mucositis. Thirteen new guidelines were developed for or against the use of various interventions in specific treatment settings, and 11 previous guidelines were confirmed after aa review of new evidence. Thirteen previously established guidelines were carried over because there was no new evidence for these interventions. Conclusions: The updated MASCC/ISOO Clinical Practice Guidelines for mucositis provide professional health caregivers with a clinical setting‐specific, evidence‐based tool to help with the management of mucositis in patients who have cancer.

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Metadata

Authors
Elad, S., Cheng, K. K. F., Lalla, R. V., Yarom, N., Hong, C., Logan, R. M., Bowen, J., Gibson, R., Saunders, D. P., Zadik, Y., Ariyawardana, A., Correa, M. E., Ranna, V., Bossi, P., & for the Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO)
Venue
Cancer
Publisher
Wiley
Published
2020-07-28
Volume
126
Issue
19
Pages
4423-4431
ISSN
  • 0008-543X (ISSN-L)
  • 1097-0142
OpenAlex
W2158334747
Cited by
1,336
References
1
FWCI
61.20
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. https://app.cochat.ai/papers/10.1002/cncr.33100
The paper
Elad, S., Cheng, K. K. F., Lalla, R. V., Yarom, N., Hong, C., Logan, R. M., Bowen, J., Gibson, R., Saunders, D. P., Zadik, Y., Ariyawardana, A., Correa, M. E., Ranna, V., Bossi, P., & for the Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO). (2020). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. https://doi.org/10.1002/cncr.33100

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.